Change of intestinal mucosa barrier function in the progress of non-alcoholic steatohepatitis in rats

Table 1 Level of serum TG,TC, ALT and AST (mean ± SD, n = 8)

Group	Time (wk)	TG (mmol/L)	TC (mmol/L)	ALT (U/L)	AST (U/L)
Control	8	0.72 ± 0.17	1.21 ± 0.29	39.00 ± 7.46	134.88 ± 35.11
Model		0.79 ± 0.20	1.78 ± 0.35a	61.75 ± 15.85a	96.63 ± 52.80a
Control	12	0.76 ± 0.17	1.26 ± 0.25	41.88 ± 6.27	138.00 ± 36.70
Model		0.85 ± 0.18	1.99 ± 0.26a	87.75 ± 26.89a	248.88 ± 53.09

^aP < 0.05 vs control group.

Table 2 Level of serum D-xylose, endotoxin and intestine mucus sIgA (mean ± SD, n = 8)

Group	Time (wk)	D-xylose (mmol/L)	SIgA (&mgr;g/mg)	Endotoxin (EU/mL)
Control	8	0.65 ± 0.21	1.72 ± 0.67	0.267 ± 0.022
Model		0.71 ± 0.17	1.55 ± 0.58	0.272 ± 0.021
Control	12	0.72 ± 0.23	1.64 ± 0.60	0.270 ± 0.023
Model		1.33 ± 0.37a	0.78 ± 0.27a	0.302 ± 0.020a

^aP < 0.05 vs control group.

Table 3 Level of SOD and MDA in small intestine tissue SOD and MDA (mean ± SD, n = 8)

Group	Time (wk)	SOD (U/mgprot)	MDA (nmol/mgprot)
Control	8	83.29 ± 10.56	0.55 ± 0.06
Model		71.61 ± 9.28a	0.72 ± 0.05a
Control	12	80.79 ± 7.76	0.59 ± 0.04
Model		61.26 ± 7.01c	0.93 ± 0.08c

^aP < 0.05,

^cP < 0.05 vs control group.