Clear cell colitis: A form of microscopic colitis in children

Table 1 Expression of immunocytochemical markers in the CCC of the colon submucosa including some histological staining

Marker	Clear cells
CD3 (T cell)	Negative
CD4 (T cell)	Negative
CD22 (B cell)	Negative
CD34 (precursor cell)	Negative
CD31 (Endothelial)	Negative
CD68 (Macrophages)	+++ Strongly positive
PCNA-proliferation antigen	Negative2
Ki67 mitotic activity	Negative1
Chromogranin	Negative
Synaptophysin	Negative
Naurofilament	Negative
Actin	Negative
P53 mutations	Negative
GFAP glial marker	Negative
TNF alpha	Negative
IL2	Negative
Mucicarmin	Negative
PAS	Strong positive
PAS diastase	Digested
Osmium tetraoxide	Positive

¹1-3 per crypt;

²Positive in the cryptic epithelium.