Proton pump inhibitors in cirrhosis: Tradition or evidence based practice?

Table 1 Prevalence of peptic ulcer in patients with liver cirrhosis

Investigator	Number of patients	Gastric ulcer prevalence (%)
Siringo, 1995	324	4.6
Chen, 1996	245	20.8
Tsai, 1998	130	16.1
Kirk, 1980	163	14.7
Rabinovitz, 1990	216	7.8

Table 2 Gastric and duodenal ulcer in patients with liver cirrhosis according to the severity of portal hypertension (from Wu et al 1995)

	Controls (n = 60)		Compensated cirrhosis (n = 60)		Decompensated cirrhosis (n = 60)		P
	n	%	n	%	n	%
Duodenal ulcer	2	3.3	10	16.7	8	13.3	0.046
Gastric ulcer	1	1.7	2	3.3	9	15.0	0.006
All ulcers	3	5.0	12	20.0	17	28.3	0.003