Endoscopic submucosal dissection for gastrointestinal neoplasms

Table 1 Recent outcomes of various endoscopic submucosal dissection methods for stomach, esophagus and colorectum

Site	Author	Yr	Method	En bloc resection rate (%)	Local recurrence rate (%)
Stomach	Yamamoto[33]	2002	EMRSH	76	3
				(53/70)	(2/67)
	Ishigooka[34]	2004	s-ERHSE	79	0
				(27/34)	(0/34)
	Oda[35]	2005	ESD-IT knife	931	-
				(957/1033)
	Kakushima[32]	2006	ESD-Flex knife	911	-
				(347/383)
	Imagawa[36]	2006	ESD-Flex knife	841	0
				(181/195)	(0/164)
	Oyama[37]	2006	ESD-Hook knife	94	0
				(104/111)	(0/111)
	Onozato[38]	2006	ESD-Flex knife	941	0
				(161/171)	(0/99)
	Hirasaki[39]	2007	ESD-IT knife	96	-
Esophagus	Oyama[8]	2005	ESD-Hook knife	95	0
				(95/102)	(0/102)
	Fujishiro[11]	2006	ESD-Flex knife	100	2.5
				(58/58)	(1/40)
Colorectum	Fujishiro[31]	2007	ESD-Flex knife	91.5	1.8
				(183/200)	(2/111)
	Saito[40]	2007	ESD several knives	84	0.5
				(168/200)	(1/180)
	Tanaka[41]	2007	ESD several knives	80	0
				(56/70)	(0/62)
	Tamegai[42]	2007	ESD-Hook knife	98.6	11
				(33/42)	(4/36)
	Onozato[43]	2007	ESD-Flex knife	77	0
				(27/35)	(0/23)

¹En bloc resection + R0 resection rate.

Table 2 Bleeding and perforation rate of various endoscopic submucosal dissection methods for stomach, esophagus and colorectum

Site	Author	Year	Method	Total cases	Bleeding (%)	Perforation (%)
Stomach	Yamamoto[33]	2002	EMRSH	70	4	0
	Ishigooka[34]	2004	s-ERHSE	34	0	12
	Oda[35]	2005	ESD-IT knife	1 033	6	4
	Kakushima[32]	2006	ESD-Flex knife	383	3.4	3.9
	Imagawa[36]	2006	ESD-Flex knife	159	0	6.1
	Oyama[37]	2006	ESD-Hook knife	111	-	1
	Onozato[38]	2006	ESD-Flex knife	171	7.6	3.5
	Hirasaki[39]	2007	ESD-IT knife	112	4	1
Esophagus	Oyama[8]	2005	ESD-Hook knife	102	-	0
	Fujishiro[11]	2006	ESD-Flex knife	58	0	6.9
Colorectum	Fujishiro[31]	2007	ESD-Flex knife	200	1	6
	Saito[40]	2007	ESD-several knives	200	2	5
	Tanaka[41]	2007	ESD-several knives	70	1.4	10
	Tamegai[42]	2007	ESD-Hook knife	74	-	1.4
	Hurlstone[50]	2007	ESD-Flex knife	42	12	2.4
	Onozato[43]	2007	ESD-Flex knife	35	0	2.9