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©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Feb 21, 2007; 13(7): 1112-1118
Published online Feb 21, 2007. doi: 10.3748/wjg.v13.i7.1112
Published online Feb 21, 2007. doi: 10.3748/wjg.v13.i7.1112
Groupserial | Treatment and dose(mg/kg, body weight/day) | Histopathological changes | |||||||
Congestion | Haemorrhage | Edema | Necrosis | Inflammatorychanges | Dysplasticchanges | Erosions | Ulceration | ||
1 | Control (distilled water) | - | - | - | - | - | - | - | - |
(1 mL/rat) | |||||||||
2 | Ethanol, 80% (1 mL/rat) | ++ | +++ | ++ | ++ | + | + | +++ | + |
3 | Pimpinella anisum | + | + | + | - | - | - | + | - |
(250) + ethanol, 80% (1 mL/rat) | |||||||||
4 | Pimpinella anisum | + | + | + | - | - | - | + | - |
(500) + ethanol, 80% (1 mL/rat) |
Group | Treatment and dose | NP-SH concentration |
serial | (mg/kg, body weight) | (μmol/100 mg wet tissue) |
1 | Control (distilled water, 1 mL/rat) | 11.70 ± 0.86 |
2 | Control (80% ethanol, 1 mL/rat) | 6.31 ± 0.23b |
3 | Pimpinella anisum (250) + 80% ethanol (1 mL/rat) | 6.71 ± 0.33 |
4 | Pimpinella anisum (500) + 80% ethanol (1 mL/rat) | 7.68 ± 0.37a |
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Citation: Al Mofleh IA, Alhaider AA, Mossa JS, Al-Soohaibani MO, Rafatullah S. Aqueous suspension of anise “
Pimpinella anisum ” protects rats against chemically induced gastric ulcers. World J Gastroenterol 2007; 13(7): 1112-1118 - URL: https://www.wjgnet.com/1007-9327/full/v13/i7/1112.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i7.1112