Validity and cost comparison of 14carbon urea breath test for diagnosis of H Pylori in dyspeptic patients

Table 1 Patient demographics and results of H Pylori detection by various tests (n = 94), mean ± SD

Parameters	n (%)
Gender
Male	60 (64)
Female	34 (36)
Age (yr)	40.8 + 12.8
Histopathology
Positive	66 (70)
Negative	28 (30)
UBT
Positive	63 (67)
Negative	31 (33)
Rapid urease test
Positive	61 (65)
Negative	33 (35)

Table 2 Sensitivity and specificity of ¹⁴C UBT against histopathology and rapid urease test for H Pylori diagnosis (n = 94)

UBTcompared to:	Sensitivity(95% CI)	Specificity(95% CI)	PPV(95% CI)	NPV(95% CI)	Accuracy
Histopathology	92% (87-95)	93% (79-99)	97% (91-99)	84% (72-89)	93%
Rapid urease test	98% (93-99)	91% (80-94)	95% (89-97)	97% (86-99)	96%

UBT: urea breath test; PPV: positive predictive value; NPV: negative predictive value; CI: confidence interval.

Table 3 Discordant results between histopathology, ¹⁴C UBT and rapid urease test for H Pylori diagnosis (n = 94)

Groups	Patients (n)	Histopathology	UBT	RUT
Group 1	59	+	+	+
	2	+	+	-
	1	+	-	+
	4	+	-	-
Group 2	1	-	+	+
	1	-	+	-
	26	-	-	-

UBT: urea breath test; RUT: rapid urease test; +: positive; -: negative.