Endoscopic sphincterotomy in patients with stenosis of ampulla of Vater: Three-year follow-up of exocrine pancreatic function and clinical symptoms

Table 1 ERCP findings in 60 patients

	Patients n (%)
Papilla
Papillitis (chronic/acute)	20 (33)
Periampullary diverticulum	7 (12)
Pancreas
Pancreas divisum	0
Pancreatitis Cambridge 0	2 (3)
Pancreatitis Cambridge I	11 (18)
Pancreatitis Cambridge II	25 (42)
Pancreatitis Cambridge III	10 (17)
No pancreatogram	12 (20)
Bile duct system
Cholangitis	10 (17)
Biliary sludge and stones	15 (25)
Bile duct dilation (any)	31 (52)
Common bile duct stenosis	4 (6 )
Negative cholecystography	7 (12)

Table 2 Amount and kind of sphincterotomies in 60 patients

	Patients n (%)
Biliary sphincterotomy	35 (58)
Pancreatic spincterotomy	3 (5)
Both	22 (37)
Amount of necessary sphincterotomies
One	34 (57)
Two	10 (17)
Three	9 (15)
Four and more	7 (12)

Table 3 Levels of GGT, AP, bilirubin, serum lipase and serum alpha-amylase in all patients (n = 60) prior to and after endoscopic sphincterotomy (mean ± SD)

	Prior to ES	After ES	P
GGT (U/L )	102.13 ± 146.21	41.02 ± 69.24	= 0.001
	(range 4-711)	(range 7-337)
AP (U/L )	205.23 ± 214.88	146.62 ± 135.2	= 0.001
	(35-1645)	(36-1047)
Bilirubin (mg/dL)	1.4 ± 2.44	0.65 ± 0.75	< 0.001
	(0.3-15.0)	(0.1-6.0)
Serum lipase (U/L )	817.37 ± 1391.45	29.60 ± 13.18	< 0.001
	(11-7200)	(6-71)
Serum amylase (U/L )	192.92 ± 336.44	61.63 ± 19.98	< 0.05
	(15-1714)	(21-102)

ES: Endoscopic sphincerotomy.