Cytomegalovirus infection in severe ulcerative colitis patients undergoing continuous intravenous cyclosporine treatment in Japan

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Feb 7, 2007 (publication date) through Nov 3, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Clinical Research

World J Gastroenterol. Feb 7, 2007; 13(5): 754-760
Published online Feb 7, 2007. doi: 10.3748/wjg.v13.i5.754

Table 1 Clinical and epidemiological characteristics of patients

	Male	Female	Total
Age, yr (median, range)	30 (18-56)	29 (8-56)	27 (8-56)
Gender	14	9	23
CMV infection diagnosed	11	7	18
Recent corticosteroid therapy	14	9	23
Outcome: Surgery	9	6	15
Ganciclovir therapy	2	1	3

Table 2 Utility of various tests for detection of infection with CMV in CyA treated patient with UC

Parameter	Real-time PCR(%)	Serum IgMantibodies (%)	Inclusion bodies in HEstained biopsy (%)
Number	18	16	4
Sensitivity	100	88.88	22.22
Specificity	100	100	100
PPV	100	100	100
NPV	100	71.4	26.3

Citation: Minami M, Ohta M, Ohkura T, Ando T, Ohmiya N, Niwa Y, Goto H. Cytomegalovirus infection in severe ulcerative colitis patients undergoing continuous intravenous cyclosporine treatment in Japan. World J Gastroenterol 2007; 13(5): 754-760
URL: https://www.wjgnet.com/1007-9327/full/v13/i5/754.htm
DOI: https://dx.doi.org/10.3748/wjg.v13.i5.754