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©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Oct 14, 2007; 13(38): 5127-5132
Published online Oct 14, 2007. doi: 10.3748/wjg.v13.i38.5127
Published online Oct 14, 2007. doi: 10.3748/wjg.v13.i38.5127
Parameter(mean ± SEM) | Control(n = 8) | NASH(n = 8) | NASH + NAC20(n = 9) |
Body mass (g) at the beginning | 239.0 ± 2.27 | 245.1 ± 1.0 | 251.4 ± 1.7 |
at 6 wk | 438.4 ± 9.7 | 197.0 ± 8.1a | 207.8 ± 6.9a |
AST (U/L) | 86.8 ± 4.3 | 53.6 ± 9.3a | 65.6 ± 8.7 |
ALT (U/L) | 40.2 ± 2.4 | 23.0 ± 1.9a | 25.4 ± 5.7a |
Cholesterol (g/L) | 71.8 ± 1.8 | 94.8 ± 3.1a | 91.4 ± 3.5a |
Triglycerides (g/L) | 90.3 ± 19.1 | 147.8 ± 32.6 | 89.2 ± 28.2 |
Group | n | Steatosis | Necroinflammation | ||||||
0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | ||
Control | 8 | 8 | - | - | - | 8 | - | - | - |
NASH | 8 | - | - | 5 | 3 | - | 5 | 2 | 1 |
NASH + NAC20 | 9 | - | 6 | 2 | 1 | 3 | 4 | 1 | 1 |
- Citation: Thong-Ngam D, Samuhasaneeto S, Kulaputana O, Klaikeaw N. N-acetylcysteine attenuates oxidative stress and liver pathology in rats with non-alcoholic steatohepatitis. World J Gastroenterol 2007; 13(38): 5127-5132
- URL: https://www.wjgnet.com/1007-9327/full/v13/i38/5127.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i38.5127