Ferucarbotran versus Gd-DTPA-enhanced MR imaging in the detection of focal hepatic lesions

Table 1 MR sequences and parameters

Sequence	TR	TE	NEX	Matrix	FOV (cm)	Thickness Intersection gap (mm) Flip angle (mm)
T2-FSE/TSE with fat suppression	3333-4000	98	2	256 × 160	36 × 36	8 2 -
GRE T1WI	150	2	1	256 × 128	36 × 36	8 2 90°
GRE T2*WI	150	11.5	1	256 × 160	36 × 36	8 2 10°

Table 2 Comparative analysis of lesion detection for 133 lesions in 59 patients using pre-contrast, ferucarbotran-enhanced, and Gd-DTPA-enhanced sequences

Sequence	n (%)
	< 1 cm	1-3 cm	> 3 cm
	(n = 44 )	(n = 68)	(n = 21 )
1 Pre-contrast T1WI GRE	15 (34.1)b	48 (70.6)b	21 (100.0)
2 Pre-contrast FSE T2WI with fat suppression	24 (54.5)b	61 (89.7)	21 (100.0)
3 Dynamic Gd-DTPA- enhanced T1WI GRE	35 (79.5)a	67 (98.5)	21 (100.0)
4 Dynamic ferucarbotran- enhanced T1WI GRE	32 (72.7)	62 (91.2)	21 (100.0)
5 Delayed ferucarbotran-enhanced FSE T2WI with fat suppression	41 (93.2)	68 (100)	21 (100.0)
6 Delayed ferucarbotran- enhanced GRE T2*WI	39 (88.6)	67 (98.5)	21 (100.0)

^aP < 0.05,

^bP < 0.01, vs (5), (6).