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©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Sep 14, 2007; 13(34): 4560-4565
Published online Sep 14, 2007. doi: 10.3748/wjg.v13.i34.4560
Published online Sep 14, 2007. doi: 10.3748/wjg.v13.i34.4560
< 30-yr-old group | ≥ 30-yr-old group | |||
Genotype B | Genotype C | Genotype B | Genotype C | |
Number of patients | 27 | 23 | 41 | 30 |
Age (yr, mean ± SD) | 21.6 ± 5.3 | 22.2 ± 4.4 | 45.5 ± 10.8 | 42.7 ± 8.7 |
Gender (Male/Female) | 19/8 | 16/7 | 37/4 | 22/8 |
HBeAg (+/-) | 24/3 | 21/2 | 4/37 | 19/11b |
Observation period | 69.0 ± 53.4 | 62.8 ± 45.9 | 77.9 ± 50.1 | 87.0 ± 50.6 |
(mo, mean ± SD) | ||||
ALT (IU/L, mean ± SD) | 266.3 ± 262.1 | 245.8 ± 292.4 | 223.1 ± 251.7 | 265.8 ± 359.8 |
Degree of fibrosis (0/1/2/3) | 4/11/5/1 | 2/13/2/2 | 6/13/10/4 | 2/13/6/7 |
< 30-yr-old group | ≥ 30-yr-old group | |||||
Variables | Relativerisk | 95% CI | P | Relativerisk | 95% CI | P |
Gender (Male/Female) | 0 | - | 0.972 | 0 | 0.000-3.993 | 0.969 |
HBeAg | ||||||
Positive | 1 | 0.028-6.469 | 0.538 | 1 | 0.185-3.250 | 0.727 |
Negative | 2.36 | 1.29 | ||||
Degree of fibrosis | ||||||
Mild-moderate | 1 | 0.080-1.030 | 0.053 | 1 | 0.296-3.238 | 0.972 |
Severe | 10.87 | 1.02 | ||||
Genotypes | ||||||
B | 1 | 0.019-2.833 | 0.258 | 1 | 0.033-0.916 | 0.039 |
C | 4.24 | 5.75 |
Genotype B Age (yr) | Genotype C Age (yr) | ||||
At entry | Developmentof LC | Outcome | At entry | Developmentof LC | Outcome |
17 M e+ | 18 e+ | 24 e- | 18 M e+ | 24 e+ | 31 e+ dead (HCC) |
23 M e+ | 27 e- | 36 e- | |||
28 M e+ | 30 e+ | 38 e- | |||
31 M e+ | 33 e+ | 40 e+ dead (hepatic failure) | |||
31 M e+ | 39 e+ | 44 e- | |||
33 M e+ | 40 e+ | 48 e+ | |||
36 M e+ | 40 e- | 46 e- | |||
38 M e+ | 45 e- | 48 e- dead (HCC) | |||
41 M e- | 48 e- | 49 e- | 41 M e+ | 43 e+ | 51 e- |
42 M e+ | 46 e- | 48 e- | |||
45 M e- | 48 e- | 49 e- dead (HCC) | |||
58 M e- | 64 e- | 70 e- | 50 M e- | 54 e- | 57 e- |
58 M e- | 72 e- | 73 e- | 50 M e- | 52 e- | 53 e- dead (hepatic failure) |
60 M e- | 61 e- | 66 e- | |||
66 M e- | 70 e- | 71 e- | 73 F e+ | 79 e+ | 90 e+ |
- Citation: Maeshiro T, Arakaki S, Watanabe T, Aoyama H, Shiroma J, Yamashiro T, Hirata T, Hokama A, Kinjo F, Nakayoshi T, Nakayoshi T, Mizokami M, Fujita J, Sakugawa H. Different natural courses of chronic hepatitis B with genotypes B and C after the fourth decade of life. World J Gastroenterol 2007; 13(34): 4560-4565
- URL: https://www.wjgnet.com/1007-9327/full/v13/i34/4560.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i34.4560