Depression and anxiety levels in therapy-naïve patients with inflammatory bowel disease and cancer of the colon

Table 1 Expression of the depression symptoms according to the results from Hamilton’s Depression Inventory (IBD/CCa)

Symptom	0	1	2	3	4	Statistical analysis
Depressive mood	2/9	3/8	7/8	6/3	14/2	χ2 = 16.75, DF = 4, P = 0.002
Guilty feelings	15/23	0/4	5/3	6/0	6/0	χ2 = 18.14, DF = 4, P = 0.001
Suicide	28/29	-	2/0	-	2/1	χ2 = 2.28, DF = 2, P > 0.05
Early insomnia	17/10	2/10	13/10			χ2 = 4.48, DF = 2, P = 0.024
Transitory insomnia	15/11	3/11	14/8			χ2 = 6.77, DF = 2, P = 0.034
Late insomnia	18/12	3/7	11/11			χ2 = 2.74, DF = 2, P > 0.05
Work and life activities	13/17	5/7	5/3	7/3	2/0	χ2 = 4.91, DF = 4, P > 0.05
Retardation psychomotor	17/21	4/9	7/0	2/0	2/0	χ2 = 13.29, DF = 4, P = 0.01
Agitation	6/13	4/9	4/6	9/2	9/0	χ2 = 18.31, DF = 4, P = 0.01
Anxiety-psychological	5/14	5/8	1/4	12/4	9/0	χ2 = 19.71, DF = 4, P = 0.01
Anxiety-somatic	14/10	7/8	2/10	6/2	3/0	χ2 = 11.04, DF = 4, P < 0.05
Hypochondriasis	28/28	4/1	0/1			χ2 = 2.738, DF = 2, P > 0.05
Insight into the presence of the illness	13/8	17/6	2/16			χ2 = 17.29, DF = 4, P < 0.001
Diurnal variations of the mood	13/15	9/13	10/2			χ2 = 2.738, DF = 2, P > 0.05
Depersonalization and derealization, presence of the nihilistic ideas	24/29	5/1	1/0	2/0	-	χ2 = 6.08, DF = 3, P > 0.05
Paranoid ideas	30/29	0/1	2/0	-	-	χ2 = 2.96, DF = 2, P > 0.05
Obsessive-compulsive symptomatology	29/29	1/1	2/0			χ2 = 1.94, DF = 2, P > 0.05
Mean score ± SD						18.56 ± 877/10.83 ± 5.26; t = 4.17, DF = 60, P < 0.001
Centroids: IBD = 0.513, CCa = - 0.547 Section point (average of the centroids) = -0017						Equation for the selection: -2.033 + 0.137 × total depressive score

Table 2 Expression of the anxiousness symptoms according to the Hamilton’s Anxiety Rating Inventory (IBD/CCa)

Symptom	0	1	2	3	4	Statistical analysis
Anxious mood-greed, hopelessness	4/9	1/8	6/5	10/5	11/3	χ2 = 13.55, DF = 4, P = 0.009
Tension	4/7	1/8	6/5	10/9	11/1	χ2 = 14.69, DF = 4, P = 0.005
Fears: dark, loneliness, animals	19/26	2/1	4/2	7/0	0/1	χ2 = 10.03, DF = 4, P = 0.04
Intellectual impairments-memory problems, difficulties in communication	18/22	6/4	5/4	3/0	-	χ2 = 3.85, DF = 3, P > 0.05
Depressive aspect	5/15	3/4	4/8	6/1	2/14	χ2 = 19.003, DF = 4, P = 0.002
Somatic symptoms: muscular symptoms, sensory symptoms-tinnitus, blurred vision, attacks of heath, itching, etc., cardiovascular symptoms-tachycardia, palpitations, sense of pulsing, irregularities in heart actions, respiratory symptoms, urogenital symptoms	16/9	3/3	7/10	2/7	4/1	χ2 = 7.01, DF = 4, P > 0.05
Neurovegetative symptoms-face blushing, mouth dryness, vertigo, sweating	20/18	1/6	7/6	4/0	-	χ2 = 7.7, DF = 4, P > 0.05
Behavior during the interview-restlessness, agitation, walking around, frowned face, tense, sobbing, accelerated breathing, pallor, gulping and belching, vivid muscular reflexes, jerks, dilated pupillae, exophthalmus	4/10	0/5	8/13	10/0	10/0	χ2 = 24.06, DF = 4, P < 0.001
Mean score ± SD	16.22 ± 7.42/9.73 ± 6.03; t = 3.76, DF = 60, P < 0.01

Table 3 Major stressful events (revealed in five or more persons in at least one of the groups) in IBD and CCa suffering patients according to the Paykel’s scale

Event	IBD group (n)	CCa group (n)
Death of family members	8	7
Major financial difficulties	12	10
Business failure	5	2
Hospitalization of the family member due to serious illnesses	4	8
Frequent argues with parents	5	0
Separation from close person	7	2
Death of close friend	3	5
Minor financial difficulties	9	8
Mild organic illness	4	7
No stressful events at all	3	6

χ² = 12.83, DF = 9, P > 0.05.