Expression patterns and action analysis of genes associated with inflammatory responses during rat liver regeneration

Table 1 Expression abundance of 239 inflammatory response-associated genes during rat liver regeneration

Gene abbr.	Associatedwith others	Folddifference	Gene abbr.	Associatedwith others	Folddifference	Gene abbr.	Associatedwith others	Folddifference	Gene abbr.	Associatedwith others	Folddifference
1 Vascular reaction			S100a9		4.9	1Serpine1		16.7	Ndst1		0.5, 2.1
Adcyap1		3.5	Scube1	2b	3.2	Socs1		0.5, 2.4	Nfatc4		0.5
Alox5		0.2, 2.5	1Socs3		0.1, 2.5	Tgfb2		0.5, 2.9	Nfkb1		0.4, 2.3
Alox5ap		4.9	Stab1		0.4	Tnfrsf11b		0.3, 8.7	Nrf1		0.2, 2.4
Aoc3		6.1	Tac1		0.2	Tp53		2.9	Pap		68.6
Bdkrb2		0.4	Tlr2		10.6	Traf1		0.4	Pecam1		3.5
Cr2		6.0	Tlr4		0.5	3 Cell activation, proliferation and			Prdx5		0.5
Crp		0.5	Vps45		12.6	differentiation			Prg2		0.3
Ctsb		3.6	Zap70		0.4	a Cell activation			Prg3		0.2
Ctsc		0.4	Zfp36		0.1, 4.6	Acadm		6.9	Prkca		0.5, 4.6
Cysltr1		0.1, 2.1	b Cytokine			Adprtl1		0.5	Proc		0.3
Edg3		4.0	1A2m		0.4, 46.2	Ager	4	0.4	Procr		6.5
F2	2b	0.3	Abcb1		4.6	Ambp		5.1	Prok2		8.6
F3	2b	0.1, 2.0	Agtr1a		0.4	Aox1		0.3	Pten		0.5
Ggtla1		4.0	Atrn		4.4	Baat		0.2	Rage		0.4
Itga1		2.9	Bcl2a1		0.3, 5.3	C3		0.2	Rela	2a	0.5
Klkb1		0.4	Bdnf		0.4, 2.6	C3ar1		0.3, 2.3	Ripk2		0.4
Kng1		2.1	Casp1		3.0	C4a		0.5	Sele	3b	12.9
Ltb4r	3a	0.5, 8.7	Ccl17		0.1	C5r1		0.4, 2.6	Slpi		2.1
Nos3	2b	0.3, 2.1	Ccl19		3.9	Casp8		10.6	Sod2		5.6
Oldlr1		0.3, 6.5	Ccl2		18.5	Cd80		0.3, 3.0	Spn		0.2, 4.0
Ptafr		7.1	Ccl20		8.0	Cd86		2.6	Tgfb1		4.0
Ptger3	2a	0.2	Ccl21b		0.1, 2.0	Chuk		0.3	Tmem23		0.2, 4.3
Ptges		4.5	Ccl24		4.0	Cnr2		0.5, 2.6	1Tnf		3.2
Ptgs2		0.1, 2.1	Ccl27		0.3	Crcp		0.3	Tnfaip6		0.2, 2.1
Reg3g		0.3, 7.5	Ccl4		0.2, 3.0	Crebbp		0.1	Tnfrsf4		0.3, 2.3
Spin2a		0.2, 4.3	Ccl7		22.6	Csf2		0.3	Tnfsf11		2.3
Spink5		0.1	Ccr1		0.4, 27.9	1Ctgf		13.9	Tnfsf4		0.2, 2.3
2 Release cytokine			Cd274		0.3	Cybb	4	2.5	b Cell proliferation
a Process of release			Cklf1		8.3	Dusp1		0.4, 6.0	Akt1		3.9
Abcf1		2.1	Clec7a		0.2	Dysf		0.5, 4.9	B7h3		3.5
Abcf2		0.4	Ctla4		0.3	Fabp4		29.9	Bcl6		8.6
Abcf3		0.5, 2.3	Cxcl10		0.3, 9.2	Fos		28.4	Cd22		0.4
Adm		8.0	Cxcl12		0.2	1Foxm1		13.9	Hdac7a		0.5, 4.3
Adora2a		0.5	Cxcl16		0.3	Gal		11.3	Igh-1a		0.3
1Anxa1		4.3	Ddt		4.4	1Hgf		0.4	Il15	3a	0.4
Apoa2		2.9	Dfy		0.4, 8.5	Hmox2		0.4	Il2		0.3, 3.5
Apol3		2.6	Dmd		0.3	1Hpse		0.3, 6.3	Il4	3a,c	0.1, 2.6
App		6.4	Ebi3		0.2	Icam1		3.0	Il5	3c	3.5
Blvra		3.5	Ela2		0.5, 52.0	Ighe		0.2, 2.5	Il7	3c	2.8
C1qr1	4	5.5	F2	1	0.3	Ikbkb		0.3	Indo		0.4, 2.3
Cd163		0.2	F3	1	0.1, 2.0	Ikbkg		0.4	Odc1		3.3
Cd74		0.4	Gif		0.1	Il15	3b	0.4	Plp		0.1
Chst1		0.0	Gsk3b		0.4	Il16		0.4, 3.1	Ppara		0.3
Chst2		4.4	Hrh1		0.5, 9.9	1Il1B		0.4	Sele	3a	12.9
Col1a2		3.0	Hrh4		7.5	Il1f5		0.4, 2.8	Spp1	3c	0.5, 2.7
Col3a1		0.3, 6.5	1Ifng		6.5	Il1f8		0.5	c Cell differentiation
Crbpb		3.1	Igfbp4		0.5	Il1r1		0.5	Il12rb2		2.8
Esrra		0.2	Il17f		0.1	Il1rn		16.3	Il4	3a,b	0.1, 2.6
Fcgr1		2.6	Il6		0.3, 6.1	Il22ra2		0.1	Il5	3b	3.5
Itgb2		0.5	Il6r		3.0	IL2ra		0.3, 4.3	Il7	3b	2.8
Klrg1		0.4	Ins1		2.1	Il2rg		0.2, 5.1	Spp1	3b	0.5, 2.7
Lcn2		0.5, 257.2	Jak2		6.5	Il4	3b,c	0.1, 2.6	Stat5a		0.2
Map2k3		0.4	Jun		1.0, 6.9	Il5ra		7.0	Stat5b		0.3
Mapk1		2.7	Lif		0.4, 3.0	Itgam	4	3.4	Tslp		0.5, 6.1
Mbp		0.4	Loc297568		0.4	Lama5		3.8	4 Phagocytosis
Ms4a1	3a	0.1	Mapk8		0.5, 19.7	Lamc1		0.4, 2.5	Ager	3a	0.4
Ncf1		0.2, 3.7	1Mmp9		0.5, 9.5	Ltb4r	1	0.5, 8.7	C1qr1	2a	5.5
Nfkbiz		6.6	Nos3	1	0.3, 2.1	Mbl2		0.2	Cybb	3a	2.5
Nostrin		8.0	P2rx7		0.4, 2.5	Mcpt6		0.2	Itgam	3a	3.4
Orm1		2.8	Pbef1		8.1	Mif		3.2	Itih4		0.3
Parg		4.8	Pik3cd		0.3	Mob		7.0	Lyz		0.4, 3.7
Pla2g4b		2.0	Plaur		13.9	Ms4a1	2a	0.1	Nox1		0.3, 8.6
Psen2		0.2	Ppbp		0.1, 2.1	Ms4a2		0.4, 5.3	Nox4		0.1, 3.0
Ptger3	1	0.2	Ptgs1		0.7, 3.4	Mug1		0.1, 3.5
Reg3a		0.1, 64.0	Rgs16		0.1, 8.6	Myd88		2.1
Rela	3a	0.5	Serpinb5		0.5, 12.1	Ncr3		0.3

¹Indicates the reported genes associated with liver regeneration; the letters “a” and “b” at the top right corner of the number “2” respectively indicate “Process of release” and “Cytokine” during the process of release cytokine, the letters “a”, “b” and “c” at the top right corner of the number “3” respectively refer to “Cell activation”, “Cell proliferation” and “Cell differentiation” in the process of cell activation, proliferation and differentiation.