Rapid Communication
Copyright ©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Jul 21, 2007; 13(27): 3747-3751
Published online Jul 21, 2007. doi: 10.3748/wjg.v13.i27.3747
Table 1 Sequence analysis of hTCF-4 exons 3-9 in sporadic rectal cancer patients with MSI-H and controls
Frequency
ExonNucleotidechangeAmino acidchangeMutationtypePatients(n = 10)Controls(n = 10)
44-position
continuous
alteration1Q131TMissense50
4395delCS132IFrameshift40
4450 G > CQ150HMissense10
8868 G > AV290MMissense20
Table 2 Clinical details of 10 MSI-H rectal cancer patients
CaseAgeSexSizePathologyTNMCEA
No.(yr)(mm)stage(ng/mL)
154F20MucinousI1.55
228F50MucinousIV310.5
368F60MucinousII3.47
449F40MucinousII1.6
551M40UnmucinousII10.11
636M100MucinousII6.37
771F40UnmucinousI3.53
847M40UnmucinousIII4.96
954M80UnmucinousII4.3
1054M80UnmucinousIII5.8