Therapy of gastric mucosa associated lymphoid tissue lymphoma

Table 1 Paris staging system of primary gastrointestinal lymphomas[59]

Paris staging system1,2
T stage
TX	Lymphoma extend not specified
T0	No evidence of lymphoma
T1	Lymphoma confined to the mucosa/submucosa
T1m	Lymphoma confined to the mucosa
T1sm	Lymphoma confined to the submucosa
T2	Lymphoma infiltrates muscularis propria or subserosa
T3	Lymphoma penetrates serosa (visceral peritoneum) without invasion of adjacent structures
T4	Lymphoma invades adjacent structures or organs
N stage
NX	Involvement of lymph nodes not assessed
N0	No evidence of lymph node involvement
N13	Involvement of regional lymph nodes
N2	Involvement of intra-abdominal lymph nodes beyond the regional area
N3	Spread to extra-abdominal lymph nodes
M stage
Mx	Dissemination of lymphoma not assessed
M0	No evidence of extranodal dissemination
M1	Non-continuous involvement of separate site in gastrointestinal tract (e.g. stomach and rectum)
M2	Non-continuous involvement of other tissues (e.g. peritoneum, pleura) or organs (e.g. tonsils, parotid gland, ocular adnexa, lung, liver, spleen, kidney etc.)
B stage
BX	Involvement of bone marrow not assessed
B0	No evidence of bone marrow involvement
B1	Lymphomatous infiltration of bone marrow
TNMB	Clinical staging: status of tumour, node, metastasis, bone marrow
pTNMB	Histopathological staging: status of tumour, node, metastasis, bone marrow
pN:	The histological examination will ordinarily include 6 or more lymph nodes

¹Valid for lymphomas originating from the gastro-esophageal junction to the anus.

²In case of more than 1 visible lesion synchronously origination in the gastrointestinal tract, give the characteristics of the more advanced lesion.

³Anatomical designation of lymph nodes as 'regional' according to site: stomach: perigastric nodes and those located along the ramifications of the celiac artery in accordance with compartmentsIand II of the Japanese Society for gastric Cancer (1995).