Apoptotic cell death and its relationship to gastric carcinogenesis

Table 1 Clinical characteristics of cases

	Intestinalmetaplasia (n)	Sex (n)		Age ofcases (mean)	Number ofcases (n)
		Female	Male
Chronic gastritis	17	7	10	53.6 ± 16.0	17
Intestinal type adenocarcinoma	21	10	18	63.2 ± 10.3	28
Diffuse type adenocarcinoma	6	7	7	57.4 ± 16.6	14
Adenocarcinoma	27	23	19	53.5 ± 12.8	42

Table 2 Results of TUNEL staining and immunohistochemical data

	Chronic gastritisco-localization ofintestinal metaplasia	Adenocarcinomaco-localization ofintestinal metaplasia	P
TUNEL (mean)	0.09 ± 0.01	0.70 ± 0.03	≤ 0.05
p53			-
Positive	0	0
Negative	17	27
BCL-2			> 0.05
Positive	12	15
Negative	5	12
BAX			≤ 0.05
Positive	2	12
Negative	15	15