Clinical significance of mucosal suppressors of cytokine signaling 3 expression in ulcerative colitis

Table 1 Description of the criteria of Matts for endoscopic and histologic findings

Endoscopic Matts’ grades

Grade 1---normal

Grade 2---mild granularity of the mucosa, with mild contact bleeding

Grade 3---marked granularity and edema of the mucosa, contact bleeding, and spontaneous bleeding

Grade 4---severe ulceration of mucosa with hemorrhage

Histologic Matts’ grades

Grade 1---normal appearance

Grade 2---some infiltration of the mucosa or lamina propria with either round cells or polymorphs

Grade 3---much cellular infiltration of the mucosa, lamina propria, and submucosa

Grade 4---presence of crypt abscesses, with much infiltration of all layers of the mucosa

Grade 5---ulceration, erosion, or necrosis of the mucosa, with cellular infiltration of some or all of its layers

Table 2 Characteristics of UC patients

		Endoscopic Matts’ grade
Characteristics		1	2	3	4
n	62	19	15	26	2
Sex (male/female)	36/26	11/8	10/5	13/13	2/0
Mean age (in years) (range)	38.6	36.2	39.1	40.1	37.0
	(13-76)	(13-61)	(18-65)	(18-76)	(25-49)
Duration (in years) (range)	6.0	4.7	8.2	5.6	5.0
	(0.1-29)	(0.2-10)	(0.1-20)	(0.1-29)	(1-9)
Type
(total/left hemi/rectal)	42/10/10	14/1/4	10/4/1	17/4/5	1/1/0
Tx
Steroid	24	5	7	10	2
Azathioprine	7	3	1	2	1
Leukocytapheresis	9	3	2	3	1