Expression of ornithine decarboxylase in precancerous and cancerous gastric lesions

Table 1 Immunohistochemical assay of ODC protein in gastric precancerous and cancerous lesions

Histological grade	ODC protein expression (n)				Total	Positiverate (%)a
	–	+	++	+++
CSG	21	9	2	0	32	34.4b
CAG (without IM)	16	9	1	2	28	42.9bc
CAG (with IM)	4	2	6	3	15	73.3
DYS	2	1	4	4	11	81.8
GC	4	4	23	17	48	91.7

^aP < 0.01, by treand;

^bP < 0.01, CSG vs CAG (with IM), CSG vs DYS, CSG vs GC, CAG (without IM) vs DYS and CAG (without IM) vs GC; and

^cP < 0.05, CAG (without IM) vs CAG (with IM). CSG: chronic superficial gastritis; CAG: chronic atrophic gastritis; IM: intestinal metaplasia; DYS: dysplasia; GC: gastric cancer.

Table 2 IHC assay of ODC protein in gastric cancer

Histologicalgrade	ODC protein expression (n)				Total	Positiverate (%)
	-	+	++	+++
Well differentiated	9	1	5	2	17	47.1a
Moderately differentiated	1	3	2	4	10	90
Poorly differentiated	1	5	6	9	21	95.2

^aP < 0.05, well differentiated tissue vs either moderately or poorly differentiated tissues.