Experience with gemcitabine and cisplatin in the therapy of inoperable and metastatic cholangiocarcinoma

Table 1 Patient characteristics

Characteristics	No. of patients (n = 42)
Age (yr)
Median	51
(range)	(33-67)
Sex
Female	14 (33%)
Male	28 (67%)
ECOG performance status
0-1	35 (83%)
2	7 (17%)
Disease
Unresectable	12 (28%)
Metastatic disease	30 (72%)

Table 2 Major toxicity

Toxicity	%
Anemia grade 3/4	31/2
Neutropenia grade 3/4	19/2
Thrombocytopenia grade 3/4	5/0
Nephrotoxicity (Creatinine) grade≥2	0
Nausea/vomiting grade≥2	0
Neuropathy grade≥2	0
AST/ALT grade≥2	0