Detection of hepatitis C virus core antigen for early diagnosis of hepatitis C virus infection in plasma donor in China

Table 1 Days of the first detection for HCV RNA, HCV core antigen and HCV Ab and the intervals between them

Casenumber	Genotype	HCVRNA	HCVcoreantigen	HCVAb	HCV coreantigen toHCV Abs	HCVRNA toHCV Abs	HCVRNA toHCV coreantigen
S1	1b	29	29	74	45	45	0
S2	2a	20	20	39	19	19	0
S3	1b	18	18	50	32	32	0
S4	1b	29	33	66	33	37	4
S5	1b	18	35	69	34	51	17
S6	1b	14	14	55	41	41	0
S7	1b	16	16	59	43	43	0
S8	1b	25	40	54	14	29	15
S9	1b	15	15	33	18	18	0
S10	1b/2a	25	25	55	30	30	0
S11	1b	16	16	67	51	51	0
Average days		20.4	23.7	56.5	32.7	36	3.3

Table 2 Comparative results of HCV RNA and HCV core antigen detection in 49 serial samples from 11 plasma donors

	HCV RNA
HCV core antigen	Negative	Positive	Total
Negative	11	9	20
Positive	2	27	29
Total	13	36	49