Relationship between preoperative staging by endoscopic ultrasonography and MMP-9 expression in gastric carcinoma

Table 1 Relationship between the expression of MMP-9 protein in gastric cancer tissue and clinical pathological parameters

MMP-9proteinexpression	Well differentiated and moderatelydifferentiatedadencarcinoma	Poorly differentiated carcinoma and signet-ring cell carcinoma	T1	T2	T3	T4	N0	N+
--+	15	8	5	8	7	3	14	9
++-+++	11	29	3	7	20	10	11	29
P	< 0.05		< 0.05				< 0.05

Table 2 The preoperative EUS staging of gastric cancer and the expression of MMP-9

EUS staging	n	Accuracy of EUS	Preoperative serum level of MMP-9	Expression rate of MMP-9
		(%)	(ng/L, mean ± SD)	(%)
Depth of invasion
T1	9	87.5	188.8 ± 114.6	25
T2	14	73.3	230.5 ± 197.3	40
T3	28	85.2	271.7 ± 251.1	70
T4	12	76.9	485.6 ± 351.3	76.9
Lymphatic metastasis
N0	25	80.0	297.2 ± 201.7	40
N+	38	68.4	506.6 ± 358.7	71.1