Role of intravenously administered hyoscine butyl bromide in retrograde terminal ileoscopy: A randomized, double-blinded, placebo-controlled trial

Table 1 Indications for colonoscopy in two groups of patients n = 200

Indication	Group 1(active drug)	Group 2(placebo)	Total
Unexplained abdominal pain	55	56	111
Suspected colonic tuberculosis	14	12	26
Ulcerative colitis	11	13	24
Hematochezia	5	5	10
Fecal occult blood positive	4	6	10
Colon cancer	2	4	6
Occult gastrointestinal bleeding	2	2	4
Colonic polyp	1	2	3
Portal hypertension (colonic bleed)	2	1	3
Crohn’s disease	2	1	3

Table 2 Effect of hyoscine N-butyl bromide on the vital parameters mean ± SD

	Drug	Placebo	P
Pulse rate before administration	85.7 (4.7)	85.6 (3.8)	NS
Pulse rate after procedure	93.2 (4.9)	86.5 (3.9)	< 0.001
Highest pulse rate achieved
before ileoscopy	94	92
Highest pulse rate achieved
during ileoscopy	102	92
Po2 before administration	95.4 (1.5)	95 (1.3)	NS
Po2 after administration	94.4 (1.8)	94.6 (1.7)	NS
Minimum Po2 before ileoscopy	92	94	NS
Minimum Po2 during ileoscopy	90	90	NS