Expression of ICAM-1, HLA-DR, and CD80 on peripheral circulating CD1 α DCs induced in vivo by IFN-α in patients with chronic hepatitis B

Table 1 Effects of IFN- α on CD1 α DC in peripheral blood with chronic hepatitis B

Percentage of CD1 α DC
Group	n	Pre-therapy	Post-therapy	P
IFN-α	22	0.70±0.29%	1.27 ± 0.38%	< 0.05
Control	16	0.63±0.17%	0.72±0.22%	>0.05

Table 2 Effects of IFN-α on immune related molecules on CD1 α DC in peripheral blood of patients pre- and post-therapy

Group	n	ICAM-1		HLA-DR		CD80
		Pre-	Post-	Pre-	Post-	Pre-	Post-
IFN-α	22	54.97±5.95%	70.61±5.72%a	44.84±9.14%	57.86±7.78%a	33.97±8.37%	43.41±8.13%a
Control	16	60.17±4.83%	59.90±4.83%	45.01±9.08%	40.50±9.47%	33.42±11.58%	34.80±6.01%

^aP < 0.05 vs pre-therapy.