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©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Feb 28, 2006; 12(8): 1281-1286
Published online Feb 28, 2006. doi: 10.3748/wjg.v12.i8.1281
Published online Feb 28, 2006. doi: 10.3748/wjg.v12.i8.1281
Table 1 Prevalence of each type of gallstone disease among 2386 Chinese subjects
| Variable | Gallstone disease | |||
| Totalscreenednumber | Single stoneprevalencenumber(%) | Multiple stonesprevalencenumber(%) | Cholecystectomyprevalencenumber(%) | |
| Gender | ||||
| Male | 1235 | 21(1.7) | 21(1.7) | 17(1.4) |
| Female | 1151 | 19(1.7) | 34(3.0) | 14(1.2) |
| P-value for χ2-test | 0.95 | 0.04 | 0.76 | |
| Age | ||||
| <40 | 745 | 4(0.5) | 5(0.7) | 2(0.3) |
| 40-49 | 723 | 6(0.8) | 7(1.0) | 6(0.8) |
| 50-59 | 504 | 11(2.2) | 21(4.2) | 8(1.6) |
| 60-69 | 252 | 7(2.8) | 17(6.8) | 6(2.4) |
| 70+ | 162 | 12(7.4) | 5(3.1) | 9(5.6) |
| P-value for Cochran-Armitage trend test | <0.0001 | <0.0001 | <0.0001 | |
| Total | 2386 | 40(1.7) | 55(2.3) | 31(1.3) |
Table 2 Comparison of characteristics in subjects with and without gallstone disease
| Variable | Any type of gallstone disease | |||
| Yes(n=126)Mean ± SD | No(n=2260)Mean ± SD | Total(n=2386)Mean ± SD | P-valuefor t test | |
| Age (yr) | 58.63 ± 13.04 | 46.57 ± 13.22 | 47.21 ± 13.48 | <0.0001 |
| BMI (kg/m2) | 24.83 ± 3.64 | 23.50 ± 3.55 | 23.57 ± 3.57 | <0.0001 |
| FPG (mg/dL) | 109.22 ± 33.21 | 96.98 ± 25.21 | 97.63 ± 25.84 | <0.0001 |
| SBP (mmHg) | 130.06 ± 20.07 | 122.55 ± 18.40 | 122.94 ± 18.56 | <0.0001 |
| DBP (mmHg) | 81.27 ± 12.22 | 79.56 ± 12.56 | 79.65 ± 12.55 | 0.14 |
| Cholesterol (mg/dL) | 216.93 ± 41.06 | 210.51 ± 37.72 | 210.87 ± 37.94 | 0.07 |
| Triglyceride (mg/dL) | 143.39 ± 98.63 | 130.12 ± 108.06 | 130.86 ± 107.58 | 0.18 |
| HDL (mg/dL) | 57.02 ± 16.55 | 57.69 ± 15.76 | 57.65 ± 15.80 | 0.64 |
| BUN (mg/dL) | 14.94 ± 6.28 | 13.55 ± 5.56 | 13.63 ± 5.61 | 0.02 |
| Creatinine (mg/dL) | 1.08 ± 0.35 | 1.04 ± 0.40 | 1.04 ± 0.40 | 0.29 |
| Uric acid (mg/dL) | 6.74 ± 1.67 | 6.59 ± 1.72 | 6.60 ± 1.72 | 0.35 |
| AST (U/L) | 32.79 ± 30.13 | 27.59 ± 17.59 | 27.88 ± 18.54 | 0.06 |
| ALT (U/L) | 37.84 ± 54.27 | 30.01 ± 34.49 | 30.45 ± 35.91 | 0.11 |
Table 3 Univariate analysis of associated clinical factors for gallstone disease among 2386 Chinese subjects
| Gallstone disease | Crude OR(95% CI) | Adjusted OR1(95% CI) | |||
| Yes(n=126) | No(n=2260) | ||||
| Gender | male | 59 | 1176 | 1.00 | - |
| female | 67 | 1084 | 1.23(0.86-1.76) | ||
| Age (yr) | <40 | 11 | 734 | 1.00 | - |
| 40-49 | 19 | 704 | 1.80 (0.85-3.81) | - | |
| 50-59 | 40 | 464 | 5.75(2.92-11.32) | - | |
| 60-69 | 30 | 222 | 9.02(4.45-18.29) | - | |
| ≥70 | 26 | 136 | 12.76(6.16-26.43) | - | |
| BMI (Kg/m2) | <24 | 57 | 1343 | 1.00 | 1.00 |
| 24-27 | 38 | 585 | 1.53(1.00-2.33) | 1.36(0.88-2.10) | |
| ≥27 | 31 | 33 | 2.20(1.40-3.46) | 2.04(1.28-3.26) | |
| FPG (mg/dL) | <110 | 93 | 2007 | 1.00 | 1.00 |
| 110-125 | 10 | 122 | 1.77(0.90-3.49) | 1.14(0.57-2.28) | |
| ≥126 | 23 | 126 | 3.95(2.42-6.45) | 1.95(1.16-3.30) | |
| High SBP | No | 93 | 1885 | 1.00 | 1.00 |
| Yes | 33 | 375 | 1.78(1.18-2.69) | 1.18(0.54-1.33) | |
| High DBP | No | 97 | 1801 | 1.00 | 1.00 |
| Yes | 29 | 459 | 1.17(0.77-1.80) | 0.95(0.61-1.48) | |
| Hypercholeste-rolemia | No | 93 | 1827 | 1.00 | 1.00 |
| Yes | 33 | 433 | 1.50(1.00-2.26) | 1.11(0.72-1.69) | |
| Hypertriglycer-idemia | No | 100 | 1946 | 1.00 | 1.00 |
| Yes | 26 | 314 | 1.61(1.03-2.52) | 1.54(0.97-2.46) | |
| Low HDL | No | 122 | 2052 | 1.00 | 1.00 |
| Yes | 4 | 208 | 0.32(0.12-0.89) | 0.62(0.22-1.73) | |
| High BUN | No | 115 | 2118 | 1.00 | 1.00 |
| Yes | 11 | 142 | 1.43(0.75-2.71) | 0.67(0.34-1.33) | |
| High creatinine | No | 118 | 2214 | 1.00 | 1.00 |
| Yes | 8 | 46 | 3.26(1.51-7.07) | 1.22(0.54-2.78) | |
| Hyperuricemia | No | 43 | 963 | 1.00 | 1.00 |
| Yes | 83 | 1297 | 1.43(0.98-2.09) | 1.18(0.80-1.75) | |
| Higher AST | No | 106 | 2095 | 1.00 | 1.00 |
| Yes | 20 | 165 | 2.40(1.45-3.97) | 1.96(1.16-3.32) | |
| Higher ALT | No | 101 | 1883 | 1.00 | 1.00 |
| Yes | 25 | 377 | 1.24(0.79-1.94) | 1.48(0.92-2.37) | |
| HBV | Negative | 113 | 1975 | 1.00 | 1.00 |
| Positive | 13 | 285 | 0.80(0.44-1.43) | 0.98(0.54-1.78) | |
| Anti-HCV | Negative | 123 | 2204 | 1.00 | 1.00 |
| Positive | 3 | 56 | 0.96(0.30-3.11) | 0.63(0.19-2.07) | |
Table 4 Multiple logistic regression of associated factors for gallstone disease among 2386 Chinese subjects
| Variable | Gallstone disease(yes vs no) | ||
| OR | 95%CI | ||
| Gender (female vs male) | 1.34 | 0.90-1.99 | |
| Age | (40-49 vs <40 yr) | 1.63 | 0.76-3.48 |
| (50-59 vs <40 yr) | 4.93 | 2.43-9.99 | |
| (60-69 vs <40 yr) | 6.82 | 3.19-14.60 | |
| (≥70 vs <40 yr) | 10.65 | 4.78-23.73 | |
| BMI | (24-27 vs <24 kg/m2) | 1.25 | 0.79-1.97 |
| (≥27 vs <24 kg/m2) | 1.74 | 1.04-2.88 | |
| FPG | (110-125 vs <110 mg/dL) | 0.96 | 0.47-1.97 |
| (≥126 vs <110 mg/dL) | 1.71 | 1.01-2.96 | |
| High SBP (yes vs no) | 1.11 | 0.53-1.51 | |
| High DBP (yes vs no) | 0.87 | 0.52-1.48 | |
| Hypercholesterolemia (yes vs no) | 0.99 | 0.64-1.53 | |
| Hypertriglyceridemia (yes vs no) | 1.25 | 0.75-2.08 | |
| Low HDL (yes vs no) | 0.5 | 0.17-1.44 | |
| High BUN (yes vs no) | 0.59 | 0.26-1.37 | |
| High creatinine (yes vs no) | 2.02 | 0.71-5.75 | |
| Hyperuricemia (yes vs no) | 0.97 | 0.64-1.46 | |
| Higher AST (yes vs no) | 2.06 | 0.99-4.31 | |
| Higher ALT (yes vs no) | 0.83 | 0.42-1.63 | |
| HBV (positive vs negative) | 0.95 | 0.52-1.76 | |
| Anti-HCV (positive vs negative) | 0.5 | 0.15-1.69 | |
- Citation: Liu CM, Tung TH, Chou P, Chen VTK, Hsu CT, Chien WS, Lin YT, Lu HF, Shih HC, Liu JH. Clinical correlation of gallstone disease in a Chinese population in Taiwan: Experience at Cheng Hsin General Hospital. World J Gastroenterol 2006; 12(8): 1281-1286
- URL: https://www.wjgnet.com/1007-9327/full/v12/i8/1281.htm
- DOI: https://dx.doi.org/10.3748/wjg.v12.i8.1281