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©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Feb 28, 2006; 12(8): 1273-1277
Published online Feb 28, 2006. doi: 10.3748/wjg.v12.i8.1273
Published online Feb 28, 2006. doi: 10.3748/wjg.v12.i8.1273
Table 1 Applied exclusion criteria
Exclusion criteria |
Acute thrombosis of portal or hepatic veins |
Any ultrasonographic (including Doppler studies) finding compatible with mass occupying lesion in liver |
Positivity of viral hepatitis markers |
Any finding in the liver biopsy suggesting parenchymal liver disease (including autoimmune liver diseases and metabolic liver diseases) |
Acquired hematological abnormality leading to thrombophilia (myeloproliferative diseases, paroxysmal nocturnal hemoglobinuria, history of use of oral contraceptive or estrogen replacement treatment, anti-phospholipid syndrome, history of cancer, history of hepatobiliary surgery, history of pancreatitis) |
Genetic hematological abnormality leading to thrombophilia (mutation of factor V Leiden, mutation of prothrombin, deficiencies in proteins C and S or antithrombin, hyperfibrinogenemia, hyperhomocysteinemia) |
Severe and widespread atherosclerosis, uncontrolled or newly diagnosed malignancy elsewhere, systemic inflammatory diseases, history of recent operation |
Table 2 General characteristics of the patients (results were given as minimum, maximum and median)
Test | Result |
Age | 28-74 (48) |
Female/Male | 6/3 |
PVT (n) | 7 |
HVT (n) | 2 |
Hemoglobin (gr/L) | 9.5-16.6 (13.5) |
Platelet (count/mL) | 62.000-358.000 (168.000) |
ALT (U/L) | 13-38 (23) |
AST (U/L) | 18-38 (27) |
ALP (U/L) | 87-355 (200) |
GGT (U/L) | 16-123 (34) |
Total Bilirubin (mg/L) | 0.24-2.08 (0.65) |
INR | 1.06-1.47 (1.14) |
Protein C (%) | 55-137 (87) |
Protein S (%) | 58-113 (85) |
AT (%) | 75-109 (90) |
Homocysteine (umol/L) | 9-19 (15) |
Fibrinogen (mg/L) | 181-420 (271) |
Table 3 Comparison of patient and control groups by advanced tests (results were given as minimum, maximum and median)
Test (normal limits) | Patient group (n) | Control group (n) | Significance |
FVIIa (25.5-96.9 mU/mL) | 27-1232 (96) | 39-325 (129) | NS1 |
Total TFPI (81.2 ± 30.4 ng/mL) | 22-114 (87.2) | 43-112 (79) | NS |
Free TFPI (10.0 ± 4.8 ng/mL) | 5-41 (19) | 9-20 (13) | aP < 0.05 |
sVCAM (395-714 ng/mL) | 489-1890 (915) | 410-890 (517) | cP < 0.05 |
sICAM (115-306 ng/mL) | 148-400 (252) | 24-260 (164) | bP < 0.05 |
E-Selectin (29.1-63.4 ng/mL) | 14-68 (20) | 11-64 (29) | NS |
Table 4 Results and comparisons of GFC (global fibrinolytic capacity)
Group | Severely low GFC | Moderately low GFC | Normal GFC |
Patient group | 0 | 4 | 5 |
Control group | 0 | 0 | 14 |
Fisher’s exact test | P < 0.05 |
- Citation: Harmanci O, Buyukasik Y, Kirazli S, Balkanci F, Bayraktar Y. Does endothelium agree with the concept of idiopathic hepatic vessel thrombosis. World J Gastroenterol 2006; 12(8): 1273-1277
- URL: https://www.wjgnet.com/1007-9327/full/v12/i8/1273.htm
- DOI: https://dx.doi.org/10.3748/wjg.v12.i8.1273