Etiology and consequences of thrombosis in abdominal vessels

Table 1 Relative risks and comparison of common thrombophilic conditions[21,22].

Thrombophilic condition	Relative risk of thrombosis
Inherited
Heterozygote deficiency of natural anticoagulants (PC, PS, AT)	10-fold
Heterozygote FVLM	5-8 fold
Homozygote FVLM	50-80 fold
Heterozygote PM	2-4 fold
Homozygote PM	10-fold
Acquired
Oral contraceptive use	4-fold
Surgery	6-fold
Immobilization	11-fold
Anti-phospholipid syndrome	10-fold
Combined
Oral contraceptive use + Heterozygote FVLM	35-fold

Table 2 Role of genetic thrombophilic factors in development of PVT

Thrombophilicfactor	Chamouradet al[41]	Egeselet al[40]	Janssenet al[39]	Denningeret al[33]	Primignaniet al[38]
n	10	32	92	36	65
FVLM	10	30	8	2,8	3
PM	40	NS1	3	14	22
PC deficiency	NS	26	7	0	0
PS deficiency	NS	43	2	30	2
AT deficiency	NS	26	1	4,5	3

All values except number of patients (n) indicate percentage of patients. ¹NS, not studied.