Flow cytometry assay of myeloid dendritic cells (mDCs) in peripheral blood during acute hepatitis C: Possible pathogenetic mechanisms

Table 1 Laboratory and immunological parameters of the enrolled patients (mean±SD, n, %)

Parameters	A-T0	A-T6	A-res	B	C
Age (yr, mean±SD)	42±2	42±3	46±5	35±3	32±5
Gender
Male (n = 9)	8/11	8/11	1/11	9/10	6/10
Female (n = 2)	0/11	0/11	2/11	1/10	4/10
ALT level (<40 U/L)	1 325±360	92±12	1 620±220	1 328±325	<40
AST level (<40 U/L)	817±435	84±9	942±160	996±73	<40
HCV-RNA (IU/mL, mean±SD)	239±2 x10^3	+	198±3 x10^3	-	-
HBsAg	-	-	-	-	-
Genotype
1	8/11	8/11	1/11	n.a.	n.a.
2a/2c	0/11	0/11	2/11	n.a.	n.a.
CD4+	993±333	850±240	850±240	558±167	922±345
CD11c+%	19±9%	17±7%	26±8%	30±5%	15±4 %
CD11c+ cells	1 220±558	1 312±345	1 760±232	1 980±311	1 350±200
Mode of infection
Sexual transmission	1/11			0
Unclear	8/11			0
Surgical procedures	2/11			0
Alimentary	0			10/10

A-T0 and A-T6 represent the data of the patients who were chronically infected after six months. T0 = at the admission; T6 = after six months; A-res= data at Time 0 of the patients who were negative for HCV-RNA and hypertransaminasemia after six months; n.a. = not applicable.