Colon cancer and the immune system: The role of tumor invading T cells

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Dec 7, 2006 (publication date) through Jan 29, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 7, 2006; 12(45): 7233-7238
Published online Dec 7, 2006. doi: 10.3748/wjg.v12.i45.7233

Table 1 Different pathways of colon cancer progression and possible therapeutic targets

Pathway	Targets
Cell cylce	p53, pRb, p16, p21, D-type cyclins
Apoptosis and survival	Bcl-2, Cox-2
Signal transduction	EGF-R, Akt, AP-1, Her2/neu, NFκB
Angiogenesis, invasion, and metastasis	VEGF, TSP-1, CXCR-4
Immunity	IL-6, TGF-β

Citation: Waldner M, Schimanski CC, Neurath MF. Colon cancer and the immune system: The role of tumor invading T cells. World J Gastroenterol 2006; 12(45): 7233-7238
URL: https://www.wjgnet.com/1007-9327/full/v12/i45/7233.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i45.7233