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©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Nov 28, 2006; 12(44): 7172-7178
Published online Nov 28, 2006. doi: 10.3748/wjg.v12.i44.7172
Published online Nov 28, 2006. doi: 10.3748/wjg.v12.i44.7172
Cut-off level | Sensitivity% (95% CI) | Specificity% (95% CI) | LR5+ | LR- | Youden’s J index | |
PG-1 (µg/L)3 | < 251 | 44 (12-77) | 95 (87-100) | 8.8 | 0.59 | 0.40 ± 0.17 |
≤ 61.52 | 78 (40-97) | 91 (71-99) | 8.6 | 0.24 | 0.69 ± 0.15 | |
PG-1/PG-23 | < 2.51 | 56 (21-86) | 100 (84-100) | ∞ | 0.44 | 0.56 ± 0.17 |
≤ 2.22 | ||||||
17-gastrin (pmol/L) | < 214 | 30 (16-58) | 86 (70-100) | 2.1 | 0.81 | 0.16 ± 0.16 |
≤ 7.524 | 90 (56-98) | 52 (30-74) | 1.89 | 0.19 | 0.42 ± 0.14 | |
> 13.323 | 67 (30-92) | 96 (77-99) | 14.7 | 0.35 | 0.62 ± 0.16 |
Characteristics | Estimated gastric cancer risk | Total(n = 536) | ||
Low (A)(n = 115) | Medium (B)(n = 354) | High (C)(n = 67) | ||
Corpus atrophy1 | Absent | Absent | Present | |
H pylori infection2 | Absent | Present | Present or absent | |
Men, n (%) | 46 (40.0) | 168 (47.5) | 35 (52.2) | 249 (46.5) |
Age (yr)a, (mean ± SD) | 49.6 ± 22.2 | 48.6 ± 18.0 | 61.9 ± 13.3 | 50.5 ± 19.0 |
Educational level (yr)a, (mean ± SD) | 8.8 ± 5.2 | 8.2 ± 4.3 | 5.8 ± 4.2 | 8.0 ± 4.6 |
Rurality, n (%) | 27 (23.5) | 99 (28.0) | 22 (32.8) | 148 (27.6) |
Living in high-risk counties, n (%) | 39 (33.9) | 146 (41.2) | 24 (35.8) | 209 (39.0) |
17-Gastrina (pmol/L), (mean ± SD) | 4.1 ± 6.8 | 5.6 ± 7.1 | 14 ± 14.3 | 6.3 ± 8.8 |
- Citation: Rollan A, Ferreccio C, Gederlini A, Serrano C, Torres J, Harris P. Non-invasive diagnosis of gastric mucosal atrophy in an asymptomatic population with high prevalence of gastric cancer. World J Gastroenterol 2006; 12(44): 7172-7178
- URL: https://www.wjgnet.com/1007-9327/full/v12/i44/7172.htm
- DOI: https://dx.doi.org/10.3748/wjg.v12.i44.7172