Evaluation of the role of H pylori infection in pathogenesis of gastric cancer by immunoblot assay

Table 1 Positive rate (%) of different reaction bands in the two groups of patients

	Normal		CA
	Hpylori (+)	Hpylori (-)	Hpylori (+)	Hpylori (-)
n	11 (%)	14 (%)	11 (%)	18 (%)	P
Overall	100.0	14.3	100.0	88.9	< 0.0001
116 kDa	100.0	14.3	90.9	72.2	0.002
89 kDa	44.4	0.0	60.0	27.8	0.052
35 kDa	100.0	0.0	100.0	61.1	0.0003
30 kDa	100.0	7.14	81.8	58.80	0.003
26.5 kDa	90.9	14.3	72.7	66.7	0.005
19.5 kDa	72.7	0.0	40.0	16.6	0.238

Fisher’s exact test was used to test for the different positive rate between CA-H pylori (-) and Normal-H pylori (-) group.

Table 2 Positive rate (%) of the different reaction bands in the two groups of patients

	Normal		CA
	Hpylori (+)	H pylori (-)	H pylori (+)	Hpylori (-)
n	11 (%)	14 (%)	11 (%)	14 (%)	P
Overall	100.0	14.3	100.0	92.9	< 0.0001
116 kDa	100.0	14.3	90.9	71.4	0.006
89 kDa	44.4	0.0	60.0	35.7	0.04
35 kDa	100.0	0.0	100.0	57.1	0.002
30 kDa	100.0	7.14	81.8	75.1	0.01
26.5 kDa	90.9	14.3	72.7	71.4	0.006
19.5 kDa	72.7	0.0	40.0	14.3	0.482

Four H pylori (-) patients with their tumors localized in the cardia were excluded from the analysis. Fisher’s exact test was used to test for the different positive rate between CA-H pylori (-) and Normal-H pylori (-) groups.