Role of transforming growth factor-beta1-smad signal transduction pathway in patients with hepatocellular carcinoma

doi:10.3748/wjg.v12.i4.644

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Jan 28, 2006 (publication date) through Oct 31, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 28, 2006; 12(4): 644-648
Published online Jan 28, 2006. doi: 10.3748/wjg.v12.i4.644

Table 1 Expressions of TGF-β1,TβR-II in HCC and its adjacent tissue (mean ± SD)

	TGF-β1			TβR-II
	n	Average optical density	Positive area (%)	n	Average optical density	Positive area (%)
	n	(OD)	Positive area (%)	n	(OD)	Positive area (%)
HCC tissue	24	0.0704 ± 0.0116^a	63. 08 ± 12.91^b	18	0.0406 ± 0.0121^c	31.33 ± 16.35^d
Adjacent tissue	24	0.0462 ± 0.0110	24.04 ± 16.68	18	0.0639 ± 0.0129	58.33 ± 11.48

t = 7.39,

^aP<0.01 vs adjacent tissue; t = 9.24,

^bP<0.01 vs adjacent tissue; t = 5.58,

^cP<0.01 vs adjacent tissue; t = 5.74,

^dP<0.01 vs adjacent tissue.

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Table 2 Relationship between expressions of TGF-β1 and TβR-II in HCC tissue

		TGF-β1		Total
		+	−
	+	10	8	Total	18
TβR-II
	−	14	4	18
Total		24	12	36

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Table 3 Comparison of MVD in HCC and its adjacent tissue (mean ± SD)

	n	MVD
HCC tissue	36	32.45 ± 10.62
Adjacent tissue	36	4.62 ± 1.67

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Citation: Ji GZ, Wang XH, Miao L, Liu Z, Zhang P, Zhang FM, Yang JB. Role of transforming growth factor-beta1-smad signal transduction pathway in patients with hepatocellular carcinoma. World J Gastroenterol 2006; 12(4): 644-648
URL: https://www.wjgnet.com/1007-9327/full/v12/i4/644.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i4.644