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©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Oct 21, 2006; 12(39): 6361-6365
Published online Oct 21, 2006. doi: 10.3748/wjg.v12.i39.6361
Published online Oct 21, 2006. doi: 10.3748/wjg.v12.i39.6361
iNOS polymorphism | n | GA n (%) | OR | 95% CI |
C/C | 217 | 121 (55.8) | 1.00 | Reference |
C/T | 30 | 16 (53.3) | 0.90 | 0.42-1.94 |
T/T | 3 | 0 (0) | 0 | - |
C/T+T/T | 33 | 16 (48.5) | 0.75 | 0.36-1.56 |
iNOS polymorphism | Cases1n (%)(n = 201) | Controls n (%)(n = 454) | OR | 95% CI |
C/C | 175 (87.1) | 403 (88.8) | 1.00 | Reference |
C/T | 25 (12.4) | 48 (10.6) | 1.22 | 0.69-2.17 |
T/T | 1 (0.50) | 3 (0.66) | 0.71 | 0.07-7.54 |
C/T + T/T | 26 (12.9) | 51 (11.2) | 1.19 | 0.68-2.08 |
Polymorphism | Phenotype1 | Total cases2n (%) | OR | 95% CI | Non-cardia n (%) | OR | 95% CI | Cardia n (%) | OR | 95%CI |
(n = 185) | (n = 177) | (n = 8) | ||||||||
C/C | Differentiated | 93 (82.3) | 1.00 | 86 (81.9) | 1.00 | 7 (87.5) | 1.00 | |||
C/T | Differentiated | 20 (17.7) | 2.02 | 1.04-3.92a | 19 (18.1) | 2.13 | 1.08-4.18a | 1 (12.5) | 1.28 | 0.15-11.0 |
T/T | Differentiated | 0 (0) | 0 | 0 (0) | 0 | 0 (0) | 0 | |||
C/T + T/T | Differentiated | 20 (17.7) | 1.84 | 0.96-3.54 | 19 (18.1) | 1.94 | 1.00-3.78a | 1 (12.5) | 1.16 | 0.14-9.95 |
C/C | Undifferentiated | 69 (95.8) | 1.00 | 69 (95.8) | 1.00 | 0 | - | |||
C/T | Undifferentiated | 2 (2.78) | 0.25 | 0.06-1.06 | 2 (2.78) | 0.25 | 0.06-1.06 | 0 | - | |
T/T | Undifferentiated | 1 (1.39) | 1.74 | 0.17-18.1 | 1 (1.39) | 1.74 | 0.17-18.1 | 0 | - | |
C/T + T/T | Undifferentiated | 3 (4.17) | 0.35 | 0.10-1.17 | 3 (4.17) | 0.35 | 0.10-1.17 | 0 | - |
- Citation: Goto Y, Ando T, Naito M, Goto H, Hamajima N. Inducible nitric oxide synthase polymorphism is associated with the increased risk of differentiated gastric cancer in a Japanese population. World J Gastroenterol 2006; 12(39): 6361-6365
- URL: https://www.wjgnet.com/1007-9327/full/v12/i39/6361.htm
- DOI: https://dx.doi.org/10.3748/wjg.v12.i39.6361