Elevated risk for gastric adenocarcinoma can be predicted from histomorphology

Table 1 Gastric cancer mortality in different populations (Modified from Winawer et al[3])

Countries	Yr	Yr
	2000	2020
Developed	334.000	440.000
Developing	543.000	983.000

Table 2 Gastric cancer risk index in patients with active H pylori gastritis

Grade of gastritis (infiltration by lymphocytes and plasma cells) is more severe in the corpus compared to the antrum or at least equally distributed

Activity of gastritis (infiltration by neutrophilic granulocytes) is more severe in the corpus compared to the antrum or at least equally distributed

Intestinal metaplasia present in the antrum and/or in the corpus

Each feature is scored with one point. Values between 0 and 3 and a total sum of 3 are possible (Adapted from Meining et al[16]).

Table 3 Prevalence of H pylori-associated high risk gastritis (3-index-points) in relation to age (n = 845) (Modified from Leodolter et al[19])

Age	n	3-index-points
< 35 yr	114	0.9%
35-54 yr	116	2.7%
55-64 yr	186	6.5%
65-74 yr	145	12.7%
> 74 yr	83	12.6%