Timing of laparoscopic cholecystectomy for acute cholecystitis: A prospective non randomized study

Table 1 Impact of delay in laparoscopic cholecystectomy on outcomes

Outcome	I: ≤ 3 d	II: 4-7 d	III: ≥ 8 d	P
	(n = 36)	(n = 58)	(n = 35)
Conversion rate	1 (2.8%)	2 (3.4%)	3 (8.5%)	NS
Mortality	0	0	0	NS
Morbidity	3 (8.3%)	6 (10.3%)	5 (14.2%)	NS
Postop hospital stay	2 (1-6) d	2 (1-14) d	2 (1-35) d	NS

NS: no significant difference.

Table 2 Demographic and perioperative characteristics of patients with acute cholecystitis

Characteristic	I: ≤ 3 d	II: 4-7 d	III: ≥ 8 d
	(n = 36)	(n = 58)	(n = 35)
Male / Female	15/21	19/39	16/19
Age (median)	55 (19-76) yr	65 (24-87) yrb	62 (30-81) yra
ASA (I/II/III)	18/13/5	23/25/10	14/15/6
Complicated cholecystitis	9	34b	15
Preoperative ERCP	2	10	8a
Spillage	21	39	18
Drain use	17	32	19
Operative time	55 (35-90) min	62.5 (25-120) min	72.5 (35-120) mina

^aP < 0.05,

^bP < 0.01 vs group I.

Table 3 Complications and their treatment

Group 1: ≤ 3 d (n = 36)	Group 2: 4-7 d (n = 58)	Group 3: ≥ 8 d (n = 35)
(1) Subhepatic collection	(2) Bile leaks	(2) Bile leaks
Laparoscopic drainage	ERCP and CBD stent	ERCP and CBD stent
	Spontaneous closure at 48 h
(1) Bleeding	(1) Subhepatic collections	(1) Bleeding from drain site
Laparotomy d 1	Percutanous CT guided drainage	Drain removal
	Laparotomy after failed percutaneous
(1) Wound infection (converted)	(1) Re-admission at postop day 15 with cholangitis	(1) Severe pancreatitis
Wound opening	ERCP & sphincterotomy	ICU admission
	(1) Chest infection	(1) Readmission at postop d 6 with DVT
	Antibiotics, physiothertpy	Heparin

Complications are presented with parentheses to indicate the number of patients suffered the complication; under the complication line the way of management for each case (without numbers) is presented.