Living donor liver transplantation to patients with hepatitis C virus cirrhosis

Table 1 Comparison between LDLT and DDLT for hepatitis C virus cirrhosis

Study			N		Dif1	Protocol biopsy	Findings
Author	Year	Institution	LDLT	DDLT
Gaglio[23]	2003	Colombia U.	23	45	Yes	No	Cholestatic hepatitis in 17% of LDLT and 0% of DDLT (P = 0.001). No significant difference in incidence of Rec.
Shiffman[28]	2003	Virginia Commonwealth U.	22	53	No	Yes	79% patient survival in LDLT and 91% in DDLT during 3 year (NS). No significant difference in inflammation score in liver specimen after 3 years
Russo[29]	2004	UNOS data	279	3955	No	No	87% 1-year patient survival in both.
Thuluvath[30]	2004	UNOS data	207	408	No	No	No significant difference in patient survival (P = 0.6).
Van Vlierberghe[32]	2004	Ghent U.	17	26	No	No	Rec in 35% of LDLT and 38% of DDLT during 1 year (P = 0.1)
Bozorgzadeh[34]	2004	Rochester U.	35	65	No	No	Rec in 77% of LDLT and 72% of DDLT during 1 year (NS), 89% patient survival in LDLT and 75% in DDLT during 39 mo (NS)

¹ Difference in short-term outcomes or severity of virus recurrence between living and deceased donor liver transplantation. Abbreviations: Rec, Virus recurrence; U, University; NS, not significant; UNOS, United Network for Organ Sharing.