Eradication of H pylori infection in a rural population: One-day quadruple therapy versus 7-day triple therapy

Table 1 Demographic data and patient compliance in two groups

Treatment	H pylori (+)	Age	Completed	Compliance (%)
1-d	239	39.3 ± 6.9	229 (M105, F124)	95.8
7-d	157	157± 7.3	148 (M78, F70)	94.3
Overall	396	39.4 ± 7.1	377 (M183, F194)	95.2

Table 2 Eradication of H pylori in two groups

Treatment	n	H pylori (-)	Eradication (95% CI)	P
1-d	229	64	27.95% (22.13-33.76)	< 0.01
7-d	148	103	69.59% (62.18-77.00)

Table 3 Incidence of side effects in each group

	Treatment group
Side effects	7-d n (%)	1-d n(%)
Total	148	229
Rash	8 (5.4)1	2 (0.01)
Diarrhea	12 (8.1)	10 (4.4)
Abdominal pain	3 (2.0)	10 (4.4)
Abdominal bloating	19 (12.8)1	15 (6.6)
Stool discoloration	14 (9.5)	76 (33.2)1
Headache	5 (3.4)	4 (1.75)
Dizziness	4 (2.7)	8 (3.5)
Nausea	15 (10.1)	17 (7.4)
Metallic taste	0	4 (1.75)
Loss of appetite	5 (3.4)	7 (3.1)
Increase of appetite	14 (9.5)	13 (5.7)
Disappearance of abdominal pain	1 (0.007)	1 (0.004)
Stools becoming normal	8 (5.4)1	3 (1.3)
Feeling better	3 (2.0)	17 (7.4)1

¹There was significant difference between the two groups (P < 0.05).