Expression of E-selectin, integrin β1 and immunoglobulin superfamily member in human gastric carcinoma cells and its clinicopathologic significance

Table 1 Diagnostic value of elevated E- selectin, ICAM-1 and integrin β₁ levels in prediction of gastric carcinoma

Diagnostic value	E- selectin (> 50.4 ng/mL)	ICAM-1 (> 337 ng/mL)	Integrin β1 (> 5.2μg/mL)
Sensitivity (%)	24.6	33.3	28.1
Specificity (%)	95.7	95.7	95.7
Positive prediction value (%)	87.5	90.5	88.9
Negative prediction value (%)	51.3	54.2	52.3
Predominance ratio	7.32	11.25	8.78
95% confidence region	1.57-34.15	2.46-51.42	1.9-40.73

Table 2 Variability analysis of the prognoses and predictive factors in patients with gastric carcinoma

Variables	Risk ratio	95% confidenceregion	P
Age	0.97	0.94-1.01	0.2
Sex	0.77	0.39-1.54	0.47
Tumor location (gastric antrum, gastric body or gastric cardia )	0.95	0.62-1.45	0.81
Tumour histology (intestine type and diffusion type)	1.32	0.70-2.52	0.38
Tymour differentiaton degree (high,moderate, low)	1.19	0.71-1.96	0.49
Tumour staging (stages I-IV)	2.65	1.71-4.11	0.000
T (T1-4)	2.75	1.75-4.34	0.000
N (No, N1)	4.33	1.65-11.36	0.003
M (Mo, M1)	7.36	2.98-18.2	0.000
E-selectin (elevated, normal)	2.81	1.40-5.63	0.003
ICAM-1 (elevated, normal)	2.71	1.37-5.36	0.004
Integrin β1 (elevated, normal)	2.1	1.05-4.18	0.035