Gastric signet-ring adenocarcinoma presenting with breast metastasis

Table 1 Patients’ characteristics¹ in reported cases of breast metastasis from gastric cancer

n	Reference2	Age	Histology	Presentation afterinitial diagnosis (mo)	Clinicalpresentation	Localization	Other metastatic sites
1	Reitmann 1908	33	Scirhous	-	-	R+L3	-
2	Kreibich 1909	65	Scirhous	-	-	R	Skin
3	Mourier 1910	31	Mucinous	-	-	L	Liver, pancreas
4	Stahr 1922	46	Anaplastic	-	-	R+L	-
5	Dawson 1936	25	Mucinous	-	-	R+L	Ovaries
6	Abrams 1949	-	-	-	-	-	-
7	Sandison 1959	56	Signet-ring cell	-	-	L	-
8	Hajdu 1972	-	Adenocarcinoma	-	-	L	-
9	Silverman 1974	-	Mucin-producing	Concomitant4	-	-	-
10	Toombs 1977	-	-	-	-	-	-
11	Satake 1980	39	Signet-ring cell	Concomitant	Nodule	L	-
12	Togo 1980	70	Signet-ring cell	Concomitant	Nodule	L	-
13	Nielsen 1981	59	Mucinous	Concomitant	Nodule	L	-
14	Champault 1982	65	Adenocarcinoma	Concomitant	Nodule	L	-
15	Kasuga 1986	48	Signet-ring cell	31	Nodules	R+L	-
16	Alexander 1989	28	Mucinous differentiation	Concomitant	Nodules	R+L	Lymph nodes
17	Hamby 1991	31	Signet-ring cell	Concomitant	Nodule	R	Lymph nodes, ovaries
18	Cavazzini 1993	-	Signet-ring cell	-	Inflammatory	-	-
19	Domanski 1996	48	Signet-ring cell	Concomitant	Nodule	L upper-outer	L supraclavicular
20	de la Cruz Mera 1998	61	Signet-ring cell	13	Nodule	L upper-outer	Pleura
21	Briest 1999	46	Signet-ring cell	2	Inflammatory	R+L	Bilateral axillary nodes
22	Kwak 2000	41	Signet-ring cell	Concomitant	Inflammatory	L	Ovaries5
23	Kwak 2000	23	Signet-ring cell	Concomitant	Inflammatory	R	Axillary nodes
24	Madan 2002	39	Signet-ring cell	3	Nodule	R	Ovaries, peritoneum
25	Di Cosimo 2003	39	Signet-ring cell	1	Nodules	R+L	Ovaries, peritoneum, skin
26	Boutis 2005	37	Signet-ring cell	Concomitant	Inflammatory	L	Ovaries5, ascites

¹ Clinical information is mentioned in the table only if available by the authors.

² References Reitmann 1908, Kreibich 1909, Mourier 1910, Stahr 1922, Dawson 1936, Satake 1980, Togo 1980 are included in Hamby 1991[2].

³ R: right; L: left.

⁴ Breast metastasis was the initial manifestation of disease.

⁵ No histological confirmation.