Risk factor analysis for metaplastic gastritis in Koreans

Table 1 Comparison of characteristics of normal and metaplastic gastritis (simple logistic regression model)

	Normal (%)	Metaplastic gastritis (%)	P value
Age	42.46 ± 10.15	53.20  ± 9.00	0.000
Sex			0.000
Men	3804 (36)	3983 (68)
Women	6272 (64)	1864 (32)
BMI1	24.52 ± 2.36	23.97 ± 2.86	0.208
Family history of cancer	160 (1)	125 (2)	0.065
Smoking			0.000
None or past	2933(84)	3308 (74)
Current	550 (16)	1130 (26)
Alcohol			0.059
Heavy alcoholics2	553 (15)	747 (16)
Out-eating	2477 (23)	1535 (26)	0.110
Over eating	1743 (16)	912 (15)	0.598
Irregular eating	1824 (17)	1152 (19)	0.228
Total calories	2102.94 ± 470.17	2226.46 ± 486.22	0.515
Folate	246.34 ± 91.24	289.51 ± 108.55	0.211
Salts	22.48 ± 7.27	23.02 ± 4.97	0.319
H pylori seropositivity3	4165 (39)	3566 (60)	0.007

¹BMI, body mass index.

²Over or equal 3-4 frequencies a week and ≥ 80 g once alcohol consumption is defined as the group of heavy alcoholics.

³Helicobacter pylori is abbreviated as H pylori.

Table 2 Multiple logistic regression analysis about risk factors for development of metaplastic gastritis

Variable1	Odds ratio (95% CI2)	P value
Age	8.945 (7.204-11.105)	0.000
Male gender	1.144 (1.133-1.155)	0.000
Current smoking	2.137 (1.693-2.697)	0.000
H pylori3 seropositivity	1.223 (1.049-1.426)	0.010

¹All variables in the model are as follows: age, sex, body mass index, family history of cancer, smoking, alcohol consumption, total daily calorie intake, folate intake, salt intake, dietary habit (out-eating, overeating, irregular eating), and H pylori seropositivity.

²CI, confidence interval.

³Helicobacter pylori is abbreviated as H pylori.