Effect of oral garlic on arterial oxygen pressure in children with hepatopulmonary syndrome

Table 1 Baseline characteristics of children with hepatopulmonary syndrome

	Age (yr)	Gender	Type of disease	Duration (yr)	Child score	Dyspnea
Non-responders	14	M	Cryptogenic cirrhosis	10	C	+
	10	M	AIH	5	B	-
	6	M	Biliary atresia	6	C	+
	3	F	Biliary atresia	3	C	+
	13	M	Presinusoidal	10	A	+
	12	F	Presinusoidal	9	C	+
	9	M	Biliary atresia	9	C	+
Responders	7	F	Cryptogenic	4	B	+
	12	M	Biliary atresia	11	C	+
	3	F	AIH	1	A	+
	14	M	Cryptogenic cirrhosis	9	B	+
	13	M	Presinusoidal	8	A	+
	4	M	AIH	1	A	-
	11	M	Cryptogenic cirrhosis	5	B	-
	11	F	AIH	5	A	-

AIH: Autoimmune hepatitis.

Table 2 PaO₂ values of responders and non-responders in relation to dyspnea after treatment

Responders	Baseline	1st mo	2nd mo	3rd mo	4th mo	5th mo	Dypnea after Rx
1	66	85	90	90	90	95	Improved
2	70	86	87	90	99	99	Worsened
3	74	83	85	90	90	95	Improved
4	59	79	85	95	99	99	Improved
5	43	77	79	80	80	80	Improved
6	63	85	95	95	95	95	a
7	85	91	90	92	91	95	a
8	65	69	76	84	82	80	a
Non-responders
1	34	33	32	35	40	40	No change
2	65	70	71	70	70	69	a
3	51	55	54	55	40	40	Worsened
4	57	58	.	.	.	.	Worsened
5	37	42	40	39	45	47	No change
6	45	49	51	54	50	52	No change
7	40	35	37	41	39	37	Worsened

^aNo dyspnea before and after treatment.

Table 3 PaO₂ values after oral garlic administration (mean±SD, n =15)

	Baseline	1st mo	2nd mo	3rd mo	4th mo	5th mo
Non-responders	47.1 ± 11.2	48.8 ± 13.2	47.5 ± 14.2	49 ± 13.1	47.3 ± 11.8	47.5 ± 11.8
Respondersb	65.6 ± 12.1	82 ± 6.8	85.8 ± 6.1	89.5 ± 5.1	90.7 ± 7	92.2 ± 7.7d
Total	57 ± 14.7	66.5 ± 19.7	69.4 ± 22	72.1 ± 22.6	72.1 ± 24	73 ± 24.7 d

^bP <0.01 vs non-responders,

^dP <0.01 vs baseline.