Comparison of protocatechuic aldehyde in Radix Salvia miltiorrhiza and corresponding pharmacological sera from normal and fibrotic rats by high performance liquid chromatography

Table 1 Inhibitory rates of protocatechuic aldchyde, raw Radix Salvia miltiorrhiza and corresponding normal and fibrotic drug sera on proliferation of HSCs

Group	IR (%)	A
A	24.36	1.565 ± 0.08a
(Protocatechuic aldchyde)
B	36.10	1.322 ± 0.10a
(raw Radix Salvia miltiorrhiza)
C	16.14	1.735 ± 0.12ab
(Normal drug sera of Salvia miltiorrhiza)
D	21.41	1.626 ± 0.53ab
(Fibrotic drug sera of Salvia miltiorrhiza)
E	—	2.069 ± 0.37
(Control)

^aP < 0.05 vs group E; ^bP <  0.05 vs group D IR = (experiment group–control group) ÷ control group × 100%.

Table 2 Results of sample determination (mean±SD, %)

Group	Content of protocatechuic aldehyde
Salvia miltiorrhiza Bge	0.22 ± 0.07
Normal drug sera of Salvia miltiorrhiza Bge	0.15 ± 0.01a
Fibrotic drug sera of Salvia miltiorrhiza Bge	0.19 ± 0.01ac

^aP <  0.05 vs Salvia miltiorrhiza Bge;

^cP <  0.05 vs Normal drug sera of Salia miltiorrhiza Bge.