Seroprevalence of Helicobacter pylori in dyspeptic patients and its relationship with HIV infection, ABO blood groups and life style in a university hospital, Northwest Ethiopia

Table 1 Association between socio-demographic characteristics and seropositivity for antibodies against H. pylori infection in dyspeptic patients (Northwest Ethiopia, 2003)

Characteristics	n	Serum anti-HP+[ n (%)]	Serum anti-HP- [n (%)]	OR (95% CI)	P value
Sex					0.2
Male	99	88 (88.9)	11 (11.1)	1
Female	116	96 (82.8)	20 (17.2)	0.6 (0.272,1.32)
Age group (yr)					0.2
<20	22	18 (81.8)	4 (18.2)	1
20-29	62	51 (82.3)	11 (17.7)	1.03 (0.29, 3.65)
30-39	58	47 (81.0)	11 (19.0)	0.95 (0.27, 3.37)
40-49	32	27 (84.4)	5 (15.6)	1.20 (0.28, 5.08)
50-59	27	27 (100.0)	0 (0.0)	2205.4 (0.0, 4.7E+19)
60-69	10	10 (100.0)	0 (0.0)	2205.4 (0.0, 1.5E+3)
70-79	4	4 (100.0)	0 (0.0)	2205.4 (0.0, 5.6E+45)
Occupation					0.69
Farmer	114	97 (85.1)	17 (14.9)	1
House wife	14	12 (85.7)	2 (14.3)	1.05 (0.22,5.12)
Govt employee	20	18 (90)	2 (10.0)	1.57 (0.34, 7.43)
Student	29	24 (82.8)	5 (17.2)	0.84 (0.28, 2.51)
Unemployed	14	14 (100.0)	0 (0.0)	639.67 (0.0, 3.6E+39)
Merchant	6	5 (83.3)	1 (16.7)	0.87 (0.09, 7.97)
Soldier	2	2 (100.0)	0 (0.0)	639.67 (0.0, 1.5E+39)
Others	16	12 (75.0)	4 (25.0)	0.52 (0.15, 1.82)
Address
Rural	127	109 (85.8)	18 (14.2)	1
Urban	88	75 (85.2)	13 (14.8)	0.95 (0.44, 2.06)
Marital status					0.7
Married	135	117 (86.7)	13	1
Widowed	13	11 (84.6)	2 (15.4)	0.85 (0.17, 4.13)
Divorced	22	18 (81.8)	4 (18.2)	0.69 (0.21, 2.28)
Single	39	32 (82.1)	7 (17.9)	0.70 (0.27, 1.83)
Underage	6	6(100.0)	0(0.0)	206.42 (0.0, 1.1E+15)

HP+= Helicobacter pylori positive ; HP- = Helicobacter pylori negative.

Table 2 H pylori and HIV co-infection in dyspeptic patients attending Gondar University Hospital (Northwest Ethiopia, 2003)

	H pylori		Totaln (%)	Statistics
	Seropositiven (%)	Seronegativen (%)
HIV seropositive	36 (19.6)	8 (25.8)	44 (20.5)	P = 0.4
HIV seronegative	148 (80.4)	23 (74.2)	171 (79.5)	χ2 = 0.63

Table 3 Demographic factors for HIV infection in dyspeptic patients attending Gondar University Hospital (Northwest Ethiopia, 2003)

Characteristics	HIV serostatus		P
	Seropositive n (%)	Seronegative n (%)
Male	19 (19.2)	80 (80.8)	P = 0.6
Sex			OR= 0.87 (95% CI 0.42-1.77)
Female	25 (21.6)	91 (78.4)	χ2 = 0.18
Age group (yr)
10-29	21 (25.3)	62 (74.7)	P = 0.3
30-49	17 (18.7)	74 (81.3)	χ2 = 2.23
≥ 50	6 (14.6)	35 (85.4)	γ = 2
Residence			P< 0.01
Rural	19 (15.0)	108 (85.0)	OR = 0.45 (95% CI 0.21-0.92)
Urban	25 (28.4)	63 (71.6)	χ2 = 5.78
Occupation
Farmer	18 ( 15.8)	96 (84.2)	P< 0.001
Housewife	3 (21.4)	11 (78.6)	χ2 = 24.78
Gov’t employee	2 (10.0)	18 (90.0)	γ = 7
Students	4 (13.8)	25 (86.2)
Unemployed	8 (57.1)	6 (42.9)
Merchant	4 (66.7)	2 (33.3)
Soldier	0	2 (100)
Others	5 (31.3)	11 (68.7)

Table 4 Relationship between ABO blood groups and seropositivity of antibodies against Helicobacter pylori infection

Blood group	Serum anti HP+[n (%)]	Serum anti HP- [n (%)]
O	76 (84.4)	14 (15.6)
B	59 (88.1)	8 (11.9)
A	41 (85.4)	7 (14.6)
AB	8 (80)	2 (20)
Total	184 (85.6)	31 (14.4)

Table 5 Relationship between Helicobacter pylori infection and life style in dyspeptic patients attending Gondar University Hospital (Northwest Ethiopia, 2003)

	Serum anti-HP+ n (%)	Serum anti-HP-n (%)	P value
Yes	128 (90.1)	14 (9.9)	< 0.01
Alcohol intake			χ2 = 7.05
No	56 (76.7)	17 (23.3)	γ = 1
Coffee	24 (82.8)	5 (17.2)	= 0.2
Diets Spicy food	108 (89.3)	13 (10.7)	χ2 = 3.15
Others	52 (80)	13 (20)	γ = 2