Elevated plasma cryofibrinogen in patients with active inflammatory bowel disease is morbigenous

Table 1 Plasma cryofibrinogen (CFG), fibrinogen levels and CFG/fibrinogen ratio in 284 subjects who participated in this study. When appropriate, the mean ± SD values are presented

Demography	UC			CD		Disease control			Healthy control
	UCA(n = 61)	UCR(n = 63)	UCPost-OP(n = 45)	CDA(n = 35)	CDR(n = 20)	Acute colitis(n = 10)	Collagen disease(n = 15)	Other diseases(n = 15)	(n = 20)
Age(yr)	35 ± 19	33 ± 12	36 ± 17	32 ± 11	27 ± 11	34 ± 11	38 ± 12	33 ± 16	34 ± 18
Gender(M/F)	30/31	31/32	23/22	19/16	12/8	6/4	8/7	6/9	10/10
CFG Positive(%)	87.81a	55.62	33.33	65.72b	35.03	0.0	66.72b	13.33	5.0
Fibrinogen (mg/dL)	318 ± 109	240 ± 96	303 ± 66	287 ± 137	251 ± 66	254 ± 55	384 ± 107	206 ± 96	246 ± 59
CFG/fibrinogen ratio(%)	18 ± 51a	17 ± 71a	4 ± 3	9 ± 42	4 ± 3	0	7 ± 42	6 ± 32	2.5 ± 0.7

UC: ulcerative colitis; UCA: active UC; UCR: remitted UC; CD: Crohn's disease; CDA: active CD; CDR: remitted CD; M: male; F: female; CFG positive (%): percentage of patients in whom cryofibrinogen was detected upon storage of plasma at 4°C,

¹χ² < 0.001 for active UC vs healthy control or other disease control;

²χ² < 0.01 UCR and CDA vs healthy control or other disease control;

³χ² < 0.05 UC Post OP, CDR vs healthy control or other disease;

^aχ² < 0.05 for UCA or UCR vs UCPost0OP, CDR, or other disease;

^bχ² < 0.05 for CDA, Collsgrn disease vs UCPost-OP, CDR, or other disease control.