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©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Mar 14, 2006; 12(10): 1613-1616
Published online Mar 14, 2006. doi: 10.3748/wjg.v12.i10.1613
Published online Mar 14, 2006. doi: 10.3748/wjg.v12.i10.1613
Table 1 Characteristics of the population
| Control group | Mild pancreatitis | Severe pancreatitis | P value | |
| n = | 10 | 40 | 40 | |
| Male/female | 5/5 | 27/13 | 31/9 | 0.33 |
| Age (year) | 33.5 (31.2-35.3) | 52.5 (51.5-62.7) | 58.5 (56.1-66.6) | 0.21 |
| Serum amylase (U/L) | 98 (75-128) | 356 (352-892) | 474 (451-1238) | 0.34 |
| Delay after onset (hours) | - | 20.1 (18.2-22.4) | 22.2 (19.5-23.2) | 0.58 |
| Cause of AP | ||||
| -biliary | - | 17 | 21 | 0.5 |
| -alcohol | - | 14 | 16 | 0.6 |
| -other | - | 2 | 1 | 0.6 |
| -idiopathic | - | 7 | 2 | 0.15 |
| Ranson > 3 | - | 8 | 19 | 0.017 |
| Ranson value | - | 2 (1.5-2.1) | 2 (1.9-2.6) | |
| sCD40L (pg/L) | 22 (16.3-28.1) | 795 (692-1301) | 1215 (1186-1753) | |
| CRP levels (mg/L) | 12.2 (9.3-15.5) | 42.5 (50.1-101.7) | 225.5 (199.8-319.4) | 0.0007 |
| CT scan | ||||
| -normal | - | 5 | 0 | 0.021 |
| -edematous | - | 28 | 19 | 0.04 |
| -necrosis | - | 19 | 9 | 0.02 |
| -collection | - | 8 | 27 | 0.0001 |
| Death | - | 0 | 3 | 0.07 |
Table 2 Performances of sCD40L, CRP and RANSON score
| Sensitivity(%) | Specificity(%) | Posititivepredictivevalue (%) | Negativepredictivevalue (%) | |
| sCD40L (cutoff 1 000 pg/L) | 77 | 62 | 63 | 74 |
| CRP (150 mg/L) | 72 | 81 | 80 | 74 |
| RANSON Score (>3) | 48 | 80 | 70 | 60 |
- Citation: Frossard JL, Morel P, Kwak B, Pastor C, Berney T, Buhler L, Von Laufen A, Demulder S, Mach F. Soluble CD40 ligand in prediction of acute severe pancreatitis. World J Gastroenterol 2006; 12(10): 1613-1616
- URL: https://www.wjgnet.com/1007-9327/full/v12/i10/1613.htm
- DOI: https://dx.doi.org/10.3748/wjg.v12.i10.1613