Tissue microarray for high-throughput analysis of gene expression profiles in hepatocellular carcinoma

Table 1 Expression of p21 in patients with HCC.

	n	Negative	Deletion rate (%)	χ2	P
Histology
Cancerous tissues	40	11	27.5
Para-cancerous tissues	40	2	5	7.439	<0.01
Adjacent normal liver tissues	40	1	2.5	11.174	<0.01
Grade
Well-differentiated	22	3	13.6
Poorly-differentiated	18	8	44.4	4.713	<0.05
Tumor size (diameter)
<2 cm	8	2	25
25 cm	15	4	26.7
>5 cm	17	5	29.4	0.072	>0.05

Table 2 Expression of Rb in patients with HCC.

	n	Negative	Deletion rate (%)	χ2	P
Histology
Cancerous tissues	40	17	42.5
Para-cancerous tissues	40	4	10	10.551	<0.01
Adjacent normal liver tissues	40	1	2.5	18.353	<0.01
Grade
Well-differentiated	22	10	45.5
Poorly-differentiated	18	7	38.9	0.014	>0.05
Tumor size (diameter)
<2 cm	8	3	37.5
25 cm	15	6	40
>5 cm	17	8	47.1	0.017	>0.05