Expression of p57kip2 and its relationship with clinicopathology, PCNA and p53 in primary hepatocellular carcinoma

Table 1 Relationship between p57^kip2 and pathological indexes.

Characters	p57kip2 protein expression				Positive rate (%)
	–	+	++	+++
Histological grade
I-II	2	4	5	6	88.24a
III-IV	12	0	3	0	20.00a
Clinical stage
I-II	5	2	6	5	72.22c
III-IV	9	2	2	1	35.71c
Age (yr)
<45	2	2	5	3	83.33
≥45	12	2	3	3	40
AFP (mg/L)
<400	7	3	5	6	66.67
≥400	7	1	3	0	36.36
Tumor size
<5 cm	4	3	3	3	69.23
≥5 cm	10	1	5	3	47.37
Local metastasis
Yes	7	2	4	4	58.82
No	7	2	4	2	53.33
Survival time
<1 year	11	0	4	3	38.89e
≥1 year	3	4	4	3	78.57e

^aP<0.05 vs poorly differentiated group;

^cP<0.05 vs high clinical stages;

^eP<0.05 vs poor prognosis.

Table 2 Relationship between p57^kip2, PCNA and p53.

Characters	p57kip2 Protein expression
	-	+	++	+++
PCNA
–	3	3	3	5
+	11	1	5	1
p53
–	9	1	5	2
+	5	3	3	4