Effects of Guiyuanfang and autologous transplantation of bone marrow stem cells on rats with liver fibrosis

Table 1 Effects of Guiyuanfang and BMSCs transplantation on serum ALT, AST, ALB, TP, and A/G levels.

Group	n	ALT (U/mL)	AST (U/mL)	TP (g/L)	ALB (g/L)	A/G
Control	10	38.3±5.1b	127.9±16.3b	62.6±5.9	28.8±3.5b	0.85±0.06b
Model	10	325.9±101.7	697.5±215.8	53.2±10.5	21.6±3.0	0.70±0.09
Guiyuanfang	10	56.8±11.5b	149.5±31.7b	64.0±7.0	28.3±2.6b	0.80±0.07b
BMSCs	8	67.3±22.0b	133.3±33.8b	60.6±8.8	26.1±2.2a	0.75±0.03a
Guiyuanfang plus BMSCs	8	40.4±9.5b	123.1±27.9b	57.7±5.1	26.9±4.2b	0.83±0.02b

^aP<0.05,

^bP<0.01 vs model group.

Table 2 Effects of Guiyuanfang and BMSCs transplantation on serum PCIII and HA levels.

Group	n	HA (ng/mL)	PCIII (ng/mL)
Control	10	54.61±17.04b	23.35±2.70b
Model	10	91.73±22.77	34.32±5.21
Guiyuanfang	10	47.18±10.97b	22.48±5.46b
BMSCs	8	48.96±14.79b	26.90±3.35b
Guiyuanfang plus BMSCs	8	38.24±10.34b	20.15±4.04b

^aP<0.05,

^bP<0.01 vs model group.

Table 3 Effects of Guiyuanfang and BMSC transplantation on fibrosis score.

Group	n	Grade of liver fibrosis
		0	I	II	III	IV
Control	10	8	2	0	0	0
Model	10	0	0	0	2	8
Guiyuanfang	10	0	2	5	2	1
MSCs	8	0	2	3	3	0
Guiyuanfang plus BMSCs	8	0	3	4	1	0

I = thickened perivenular collagen and a few thin collagen septa; II = thin septa with incomplete bridging between portal regions; III = thin septa and extensive bridging; IV = thickened septa with complete bridging of portal regions and a nodular appearance.