Helicobacter pylori infection, glandular atrophy and intestinal metaplasia in superficial gastritis, gastric erosion, erosive gastritis, gastric ulcer and early gastric cancer

Table 1 H pylori infection identified in different biopsy sites in associated diseases.

Endoscopical diagnosis	Cases	H pylori infective rate (%)
		Antrum	Corpus	Angle	Overall
Superficial gastritis	286	25.9	26.2	25.2	28.7
Erosive gastritis	286	46.9	53.5	49	57.7
Gastric erosion	286	52.4	61.5	52.4	63.3
Gastric ulcer	286	65	78	61.2	80.8
Early gastric cancer	286	35	50.7	34.6	52.4

Table 2 The grade of mononuclear cell infiltration, polymorphonuclear cell infiltration, glandular atrophy and intestinal metaplasia in studied patients (%).

Diagnosis	Mononuclear cell infiltration				Polymorphonuclear cell infiltration				Glandular atrophy				Intestinal metaplasia
	0	1	2	3	0	1	2	3	0	1	2	3	0	1	2	3
Superficial gastritis	40.9	34.3	10.1	14.7	72.7	3.5	4.5	19.2	78.7	17.6	2.2	1.5	85.3	4.9	4.2	5.6
Erosive gastritis	11.2	32.9	19.2	36.7	40.2	6.6	12.9	40.2	38.8	30.6	17.3	13.3	45.8	16.4	14.7	23.1
Gastric erosion	3.8	29	21	46.2	33.9	3.8	10.1	52.1	28.3	23.2	24.5	24.1	21.7	18.5	23.4	36.4
Gastric ulcer	4.2	14.3	14	67.5	17.8	3.1	7.7	71.3	29.2	17.7	21.8	31.3	21.7	2.4	2.4	73.4
Early gastric cancer	0.7	42.3	29.4	27.6	40.2	10.1	1.9	37.8	20.3	20.7	18.1	40.9	14.3	12.2	18.9	54.5

Table 3 Rates of inflammation, activity, glandular atrophy and intestinal metaplasia in patients with and without H pylori infection (%).

Diagnosis	Mononuclear cell infiltration H pylori		Polymorphonuclear cell infiltration H pylori		Glandular atrophy H pylori		Intestinal metaplasia H pylori
	Positive	Negative	Positive	Negative	Positive	Negative	Positive	Negative
Superficial gastritis	93.9b	45.1	90.2b	2.0	50.7b	9.9	34.1b	6.9
Erosive gastritis	98.8b	75.2	97.0b	9.1	76.1b	42.5	63.0b	42.1
Gastric erosion	100.0b	89.5	99.4b	8.6	84.8b	51.1	87.8b	61.9
Gastric ulcer	99.1b	81.8	99.1b	10.9	80.6b	29.8	90.9b	25.5
Early gastric cancer	100.0	98.5	100.0b	15.4	85.5	84.0	85.3	86.0

^bP<0.01 vs H pylori-negative group.