Basic Research
Copyright ©2005 Baishideng Publishing Group Inc.
World J Gastroenterol. Dec 21, 2005; 11(47): 7413-7417
Published online Dec 21, 2005. doi: 10.3748/wjg.v11.i47.7413
Table 1 The composition of synbiotics powder1
Amount/7.5 g
Thiamin (as thiamin hydrochloride)0.375 mg
Riboflavin0.425 mg
Niacin (as niacinamide)5 mg
Vitamin B6 (as pyridoxine hydrochloride)0.5 mg
Folate (as folic acid)100 μg
Vitamin B12 (as cyanocobalamin)1.57 μg
Biotin75 μg
Pantothenic acid (as d-calcium pantothenate)2.5 mg
Inulin from chicory, powdered extract (root)250 mg
Proprietary blend culture count10 billion2
Lactobacillus acidophilus and Lactobacillus bulgaricus2.7 billion
Bifidobacterium bifidum and Bifidobacterium longum6.7 billion
Streptococcus thermophilus0.6 billion
Table 2 Effect of synbiotics on feed intake in rats1
WkControl (g)Low dose (g)High dose (g)
119.9±0.619.4±1.719.8±0.7
220.0±0.119.6±1.419.9±0.2
319.9±0.419.9±0.219.9±0.2
418.5±1.518.1±0.118.9±0.2
519.9±0.319.9±0.320.0±0.4
619.9±0.119.8±0.419.8±0.5
720.0±0.120.0±0.119.8±0.8
819.9±0.320.0±0.319.4±0.3
Table 3 Effect of synbiotics on intestinal microorganisms in rats1
ControlLow doseHigh dose
Total anaerobic bacteria counts (log CFU/g)9.26±0.308.95±0.378.95±0.18
Lactobacillus (log CFU2 /g)7.42±0.449.35±0.64a9.41±0.55c
Bifidobacteria (log CFU/g)8.52±0.599.60±0.26e9.40±0.39g
Coliform organisms (log CFU/g)8.44±0.746.70±0.577.13±0.51