Risk factors for bleeding after endoscopic mucosal resection

Table 1 Baseline characteristics of study patients

	No bleeding	Bleeding
	after EMR	after EMR	P
	(n = 240)	(n = 57)
Age (yr)	65.3±9.3	66.0±8.4	0.582
Sex (M:F)	170:70	41:16:00	0.998
Tumor factors
Location
Antrum group	135 (85.4%)	23 (14.6%)	0.044
Corpus group	105 (75.5%)	34 (24.5%)
Tumor diameter (mm)	12.4±6.7	13.9±7.1	0.152
Endoscopic pattern of lesion
Elevated type	211 (83.4%)	42 (16.6%)	0.012
Depressed type	29 (65.9%)	15 (34.1%)
Histological type
Borderline adenoma	115 (82.7%)	24 (17.3%)	0.52
Cancer	125 (79.1%)	33 (20.9%)
Cutting method
Strip biopsy	156 (88.1%)	21 (11.9%)	0.001
Endoscopic aspiration mucosectomy	84 (70.0%)	36 (30.0%)

Values are mean±SE or no. of gastric lesions.

Table 2 Odds ratio of bleeding after endoscopic mucosal resection

				Crude-OR	Multiple-adjustedOR1 (95% CI)	Multiple-adjustedOR2 (95% CI)
	n	Cases	%	(95%CI)
Age (each additional year of age)	297	57	19.2	1.01 (0.98-1.05)	1.00 (0.97-1.04)	1.01 (0.97-1.04)
Tumor factors
Location of gastric lesions
Antrum group	158	23	14.6	1	1	1
Corpus group	139	34	24.5	2.24 (1.20-4.18)	2.24 (1.20-4.18)	1.69 (0.88-3.26)
Tumor diameter
Quartile 1 (4-7)	58	5	8.6	1	1	1
Quartile 2 (8-11)	89	18	20.2	3.15 (1.06-9.38)	3.15 (1.06-9.38)	3.01 (0.99-9.07)
Quartile 3 (12-15)	76	13	17.1	2.53 (0.81-7.87)	2.53 (0.81-7.87)	2.90 (0.91-9.20)
Quartile 4 (16-50)	74	21	28.4	5.35 (1.78-16.10)	5.35 (1.78-16.10)	5.63 (1.84-17.23)
P for trend				0.048	0.022	0.022
Endoscopic pattern of lesion
Elevated type	253	42	16.6	1	1	1
Depressed type	44	15	34.1	2.60 (1.28-5.26)	3.95 (1.69-9.24)	4.21 (1.75-10.10)
Histological type
Adenoma	139	24	17.3	1	1	1
Cancer	158	33	20.9	1.27 (0.71-2.27)	0.67 (0.33-1.35)	0.56 (0.27-1.16)
Cutting method
Strip biopsy	177	17	9.6	1		1
Endoscopic aspiration mucosectomy	120	40	33.3	3.18 (1.75-5.80)		3.07(1.59-5.92)

¹Adjusted for age, tumor factors, location of gastric lesions, tumor diameter, endoscopic pattern of lesion, histological type. AT indicates antrum of stomach;

²Adjusted for age, tumor factors, location of gastric lesions, tumor diameter, endoscopic pattern of lesion, histological type, and cutting method.